Sean Christensen
Overview
Explore the profile of Sean Christensen including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
761
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0
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Recent Articles
1.
Belzer A, Pach J, Mortlock R, Clune J, Olino K, Sznol M, et al.
JAAD Int
. 2023 May;
11:174-175.
PMID: 37252181
No abstract available.
2.
Ranapurwala S, Alam I, Pence B, Carey T, Christensen S, Clark M, et al.
Pharmacoepidemiol Drug Saf
. 2022 Dec;
32(5):577-585.
PMID: 36585827
Background: In the US, over 200 lives are lost from opioid overdoses each day. Accurate and prompt diagnosis of opioid use disorders (OUD) may help prevent overdose deaths. However, international...
3.
Paguigan N, Yan Y, Karthikeyan M, Chase K, Carter J, Leavitt L, et al.
ACS Chem Biol
. 2021 Aug;
16(9):1654-1662.
PMID: 34423964
Marine tunicates produce defensive amino-acid-derived metabolites, including 2-(3,5-diiodo-4-methoxyphenyl)ethan-1-amine (DIMTA), but their mechanisms of action are rarely known. Using an assay-guided approach, we found that out of the many different sensory...
4.
Hone A, Kaas Q, Kearns I, Hararah F, Gajewiak J, Christensen S, et al.
J Med Chem
. 2021 Feb;
64(3):1685-1700.
PMID: 33523678
Nicotinic acetylcholine receptors (nAChRs) are pharmacological targets for the treatment of neuropathic pain, and the α6β4 subtype has been identified as particularly promising. Rat α6β4 nAChRs are less sensitive to...
5.
Obeid J, Dahne J, Christensen S, Howard S, Crawford T, Frey L, et al.
JMIR Med Inform
. 2020 Jul;
8(7):e17784.
PMID: 32729840
Background: Suicide is an important public health concern in the United States and around the world. There has been significant work examining machine learning approaches to identify and predict intentional...
6.
Hone A, Rueda-Ruzafa L, Gordon T, Gajewiak J, Christensen S, Dyhring T, et al.
J Neurochem
. 2020 Jan;
154(2):158-176.
PMID: 31967330
Adrenal chromaffin cells release neurotransmitters in response to stress and may be involved in conditions such as post-traumatic stress and anxiety disorders. Neurotransmitter release is triggered, in part, by activation...
7.
Huynh P, Giuvelis D, Christensen S, Tucker K, McIntosh J
Mar Drugs
. 2019 Dec;
18(1).
PMID: 31877728
Chemotherapeutic drugs are widely utilized in the treatment of human cancers. Painful chemotherapy-induced neuropathy is a common, debilitating, and dose-limiting side effect for which there is currently no effective treatment....
8.
Byyny R, Martinez D, Cleary L, Ballard B, Barth B, Christensen S, et al.
Acad Med
. 2019 Nov;
95(5):670-673.
PMID: 31764080
With a motto of "Be Worthy to Serve the Suffering," Alpha Omega Alpha Honor Medical Society (AΩA) supports the importance, inclusion, and development of a culturally and ethnically diverse medical...
9.
Hone A, Fisher F, Christensen S, Gajewiak J, Larkin D, Whiteaker P, et al.
J Med Chem
. 2019 Jun;
62(13):6262-6275.
PMID: 31194549
Pharmacologically distinguishing α3β2 nicotinic acetylcholine receptors (nAChRs) from closely related subtypes, particularly α6β2, has been challenging due to the lack of subtype-selective ligands. We created analogs of α-conotoxin (α-Ctx) PeIA...
10.
Hone A, Talley T, Bobango J, Huidobro Melo C, Hararah F, Gajewiak J, et al.
J Biol Chem
. 2018 Sep;
293(46):17838-17852.
PMID: 30249616
Nicotinic acetylcholine receptors (nAChRs) containing α6 and β4 subunits are expressed by dorsal root ganglion neurons and have been implicated in neuropathic pain. Rodent models are often used to evaluate...