Scott J Dylla
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Explore the profile of Scott J Dylla including associated specialties, affiliations and a list of published articles.
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21
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3179
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Recent Articles
11.
Williams S, Anderson W, Santaguida M, Dylla S
Lab Invest
. 2013 Aug;
93(9):970-82.
PMID: 23917877
Cancer is a heterogeneous disease manifest in many forms. Tumor histopathology can differ significantly among patients and cellular heterogeneity within tumors is common. A primary goal of cancer biologists is...
12.
Hendry 2nd S, Van der Bogt K, Sheikh A, Arai T, Dylla S, Drukker M, et al.
J Thorac Cardiovasc Surg
. 2008 Oct;
136(4):1028-1037.e1.
PMID: 18954646
Objective: Mouse embryonic stem cells have demonstrated potential to restore infarcted myocardium after acute myocardial infarction. Although the underlying mechanism remains controversial, magnetic resonance imaging has provided reliable in vivo...
13.
Dylla S, Beviglia L, Park I, Chartier C, Raval J, Ngan L, et al.
PLoS One
. 2008 Jun;
3(6):e2428.
PMID: 18560594
Background: Patients generally die of cancer after the failure of current therapies to eliminate residual disease. A subpopulation of tumor cells, termed cancer stem cells (CSC), appears uniquely able to...
14.
Dalerba P, Dylla S, Park I, Liu R, Wang X, Cho R, et al.
Proc Natl Acad Sci U S A
. 2007 Jun;
104(24):10158-63.
PMID: 17548814
Recent observations indicate that, in several types of human cancer, only a phenotypic subset of cancer cells within each tumor is capable of initiating tumor growth. This functional subset of...
15.
Serafini M, Dylla S, Oki M, Heremans Y, Tolar J, Jiang Y, et al.
J Exp Med
. 2007 Jan;
204(1):129-39.
PMID: 17227908
For decades, in vitro expansion of transplantable hematopoietic stem cells (HSCs) has been an elusive goal. Here, we demonstrate that multipotent adult progenitor cells (MAPCs), isolated from green fluorescent protein...
16.
Cao F, Lin S, Xie X, Ray P, Patel M, Zhang X, et al.
Circulation
. 2006 Feb;
113(7):1005-14.
PMID: 16476845
Background: Recent studies have shown that stem cell therapy can promote tissue regeneration; however, monitoring stem cells in vivo remains problematic owing to limitations of conventional histological assays and imaging...
17.
Yamane T, Dylla S, Muijtjens M, Weissman I
Proc Natl Acad Sci U S A
. 2005 Feb;
102(9):3312-7.
PMID: 15728354
Leukemia inhibitory factor (LIF) is required, but not sufficient, for pluripotent mouse embryonic stem (ES) cell expansion in vitro in the absence of serum or a feeder cell layer, suggesting...
18.
Melikova S, Dylla S, Verfaillie C
Exp Hematol
. 2004 Nov;
32(11):1051-6.
PMID: 15539082
Objective: beta1-integrins mediate hematopoietic stem and progenitor cell homing and retention in the bone marrow (BM) and inhibit hematopoietic proliferation and differentiation. Having no intrinsic kinase activity, integrins recruit intracellular...
19.
Jamieson C, Ailles L, Dylla S, Muijtjens M, Jones C, Zehnder J, et al.
N Engl J Med
. 2004 Aug;
351(7):657-67.
PMID: 15306667
Background: The progression of chronic myelogenous leukemia (CML) to blast crisis is supported by self-renewing leukemic stem cells. In normal mouse hematopoietic stem cells, the process of self-renewal involves the...
20.
Dylla S, Deyle D, Theunissen K, Padurean A, Verfaillie C
Exp Hematol
. 2004 Mar;
32(4):365-74.
PMID: 15050747
Objective: Hematopoietic progenitor proliferation and differentiation are inhibited by integrin engagement of fibronectin (FN). Focal adhesion kinases have been shown to mediate intracellular signaling from integrins, and we recently demonstrated...