Scott C Blanchard
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Explore the profile of Scott C Blanchard including associated specialties, affiliations and a list of published articles.
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129
Citations
7715
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Recent Articles
1.
Welfer G, Brady R, Natchiar S, Watson Z, Rundlet E, Alejo J, et al.
Philos Trans R Soc Lond B Biol Sci
. 2025 Mar;
380(1921):20230379.
PMID: 40045785
Since the framing of the Central Dogma, it has been speculated that physically distinct ribosomes within cells may influence gene expression and cellular physiology. While heterogeneity in ribosome composition has...
2.
de la Rosa-Trevin J, Sharov G, Fleischmann S, Morado D, Bollinger J, Miller D, et al.
Acta Crystallogr D Struct Biol
. 2024 Oct;
80(Pt 11):780-790.
PMID: 39373194
Most scientific facilities produce large amounts of heterogeneous data at a rapid pace. Managing users, instruments, reports and invoices presents additional challenges. To address these challenges, EMhub, a web platform...
3.
Modak A, Kilic Z, Chattrakun K, Terry D, Kalathur R, Blanchard S
Annu Rev Biophys
. 2024 Jul;
53(1):427-453.
PMID: 39013028
Integral membrane proteins (IMPs) play central roles in cellular physiology and represent the majority of known drug targets. Single-molecule fluorescence and fluorescence resonance energy transfer (FRET) methods have recently emerged...
4.
Cruz-Navarrete F, Griffin W, Chan Y, Martin M, Alejo J, Brady R, et al.
ACS Cent Sci
. 2024 Jul;
10(6):1262-1275.
PMID: 38947208
Templated synthesis of proteins containing non-natural amino acids (nnAAs) promises to expand the chemical space available to biological therapeutics and materials, but existing technologies are still limiting. Addressing these limitations...
5.
Pati A, Kilic Z, Martin M, Terry D, Borgia A, Bar S, et al.
Nat Methods
. 2024 Jun;
21(7):1222-1230.
PMID: 38877317
Single-molecule fluorescence resonance energy transfer (smFRET) methods employed to quantify time-dependent compositional and conformational changes within biomolecules require elevated illumination intensities to recover robust photon emission streams from individual fluorophores....
6.
Cruz-Navarrete F, Griffin W, Chan Y, Martin M, Alejo J, Natchiar S, et al.
bioRxiv
. 2024 Mar;
PMID: 38464221
Templated synthesis of proteins containing non-natural amino acids (nnAAs) promises to vastly expand the chemical space available to biological therapeutics and materials. Existing technologies limit the identity and number of...
7.
Young P, Levring J, Fiedorczuk K, Blanchard S, Chen J
Proc Natl Acad Sci U S A
. 2024 Feb;
121(10):e2316675121.
PMID: 38422021
The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel that regulates electrolyte and fluid balance in epithelial tissues. While activation of CFTR is vital to treating cystic fibrosis,...
8.
Girodat D, Wieden H, Blanchard S, Sanbonmatsu K
Nat Commun
. 2023 Sep;
14(1):5582.
PMID: 37696823
Accurate protein synthesis is determined by the two-subunit ribosome's capacity to selectively incorporate cognate aminoacyl-tRNA for each mRNA codon. The molecular basis of tRNA selection accuracy, and how fidelity can...
9.
Levring J, Terry D, Kilic Z, Fitzgerald G, Blanchard S, Chen J
Nature
. 2023 May;
617(7961):E11.
PMID: 37142783
No abstract available.
10.
Holm M, Natchiar S, Rundlet E, Myasnikov A, Watson Z, Altman R, et al.
Nature
. 2023 Apr;
617(7959):200-207.
PMID: 37020024
In all species, ribosomes synthesize proteins by faithfully decoding messenger RNA (mRNA) nucleotide sequences using aminoacyl-tRNA substrates. Current knowledge of the decoding mechanism derives principally from studies on bacterial systems....