Peter D Kwong
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Explore the profile of Peter D Kwong including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Park J, Lindesmith L, Olia A, Costantini V, Brewer-Jensen P, Mallory M, et al.
Sci Transl Med
. 2025 Mar;
17(788):eads8214.
PMID: 40043137
Human norovirus causes more than 700 million illnesses annually. Extensive genetic diversity and a paucity of information on conserved neutralizing epitopes pose major obstacles to the design of broadly protective...
2.
Joyce M, Bu W, Chen W, Gillespie R, Andrews S, Wheatley A, et al.
Immunity
. 2025 Feb;
58(2):295-308.e5.
PMID: 39909035
Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with malignancies in humans. Viral infection of B cells is initiated by the viral glycoprotein 350 (gp350) binding to complement receptor...
3.
Morano N, Guo Y, Becker J, Li Z, Yu J, Ho D, et al.
Structure
. 2025 Jan;
33(2):228-233.e3.
PMID: 39884273
Highly pathogenic avian influenza has spilled into many mammals, most notably cows and poultry, with several dozen human breakthrough infections. Zoonotic crossovers, with hemagglutinins mutated to enhance viral ability to...
4.
Mason R, Zhang B, Morano N, Shen C, McKee K, Heimann A, et al.
Cell Rep
. 2025 Jan;
44(1):115223.
PMID: 39826122
Broadly neutralizing antibodies (bNAbs) targeting the apex of the HIV-1-envelope (Env) trimer comprise the most potent category of HIV-1 bNAbs and have emerged as promising therapeutics. Here, we investigate the...
5.
Morris D, Gorman J, Zhou T, Lora J, Connell A, Li H, et al.
bioRxiv
. 2025 Jan;
PMID: 39803442
Highlights: Out of 115 wildtype HIV-1 Env bearing SHIV infected macaques, only one macaque (T681) developed CD4bs bNAbsCD4bs bNAbs in macaque T681 recognized Env similarly to previously described CDR-H3 dominated...
6.
Gorman J, Du R, Lai Y, Ahmadi M, King H, Song K, et al.
Cell Rep
. 2025 Jan;
44(1):115163.
PMID: 39792559
The membrane-proximal external region (MPER) of the HIV-1 envelope is a target for broadly neutralizing antibodies (bnAbs), and vaccine-elicited MPER-directed antibodies have recently been reported from a human clinical trial....
7.
Mantus G, Chopde A, Gorman J, Cominsky L, Ourahmane A, Creanga A, et al.
Sci Transl Med
. 2025 Jan;
17(779):eadr8373.
PMID: 39742506
The conserved influenza hemagglutinin stem, which is a target of cross-neutralizing antibodies, is now used in vaccine strategies focused on protecting against influenza pandemics. Antibody responses to group 1 stem...
8.
Cale E, Shen C, Olia A, Radakovich N, Rawi R, Yang Y, et al.
Cell Rep
. 2024 Dec;
43(12):115010.
PMID: 39675002
Antibodies that target the gp120-gp41 interface of the HIV-1 envelope (Env) trimer comprise a commonly elicited category of broadly neutralizing antibodies (bNAbs). Here, we isolate and characterize VRC44, a bNAb...
9.
Lee M, Lu M, Zhang B, Zhou T, Katte R, Han Y, et al.
Comput Struct Biotechnol J
. 2024 Dec;
23:4192-4204.
PMID: 39640534
HIV-1 infection is initiated by the interaction between the gp120 subunit in the envelope (Env) trimer and the cellular receptor CD4 on host cells. This interaction induces substantial structural rearrangement...
10.
Reveiz M, Xu K, Lee M, Wang S, Olia A, Harris D, et al.
Front Immunol
. 2024 Nov;
15:1484029.
PMID: 39611147
Broadly neutralizing antibodies have been proposed as templates for HIV-1 vaccine design, but it has been unclear how similar vaccine-elicited antibodies are to their naturally elicited templates. To provide insight,...