Sasidhar Uppuganti
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Explore the profile of Sasidhar Uppuganti including associated specialties, affiliations and a list of published articles.
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56
Citations
771
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Recent Articles
1.
Voziyan P, Brown K, Uppuganti S, Leser M, Rose K, Nyman J
Bone
. 2024 Jul;
187:117209.
PMID: 39047900
Complications of diabetes is a major health problem affecting multiple organs including bone, where the chronic disease increases the risk of fragility fractures. One hypothesis suggests a pathogenic role for...
2.
Uppuganti S, Creecy A, Fernandes D, Garrett K, Donovan K, Ahmed R, et al.
Calcif Tissue Int
. 2024 Jul;
115(3):298-314.
PMID: 39012489
Obesity and type 2 diabetes (T2D) are risk factors for fragility fractures. It is unknown whether this elevated risk is due to a diet favoring obesity or the diabetes that...
3.
Chanbour H, Roth S, Chen J, Uppuganti S, Nyman J, Ali M, et al.
Oper Neurosurg (Hagerstown)
. 2024 Apr;
27(5):549-556.
PMID: 38651901
Background And Objectives: Optimal iliac screw position in relation to the sciatic notch remains unknown. In 12 cadavers undergoing S2 alar-iliac (S2AI) screw placement, we tested the pullout strength of...
4.
Bunn R, Adatorwovor R, Smith R, Ray P, Fields S, Keeble A, et al.
JBMR Plus
. 2023 Nov;
7(11):e10833.
PMID: 38025035
Type 1 diabetes (T1D) is associated with low bone and muscle mass, increased fracture risk, and impaired skeletal muscle function. Myostatin, a myokine that is systemically elevated in humans with...
5.
Ahmed R, Unal M, Gautam R, Uppuganti S, Derasari S, Mahadevan-Jansen A, et al.
Analyst
. 2023 Aug;
148(19):4799-4809.
PMID: 37602820
The fracture resistance of bone arises from the hierarchical arrangement of minerals, collagen fibrils (, cross-linked triple helices of α1 and α2 collagen I chains), non-collagenous proteins, and water. Raman...
6.
Gautam R, Ahmed R, Haugen E, Unal M, Fitzgerald S, Uppuganti S, et al.
Spectrochim Acta A Mol Biomol Spectrosc
. 2023 Aug;
303:123240.
PMID: 37591015
Since spatially offset Raman spectroscopy (SORS) can acquire biochemical measurements of tissue quality through light scattering materials, we investigated the feasibility of this technique to acquire Raman bands related to...
7.
Voziyan P, Uppuganti S, Leser M, L Rose K, Nyman J
BBA Adv
. 2023 Apr;
3:100079.
PMID: 37082268
Accumulation of advanced glycation end products (AGEs), particularly in long-lived extracellular matrix proteins, has been implicated in pathogenesis of diabetic complications and in aging. Knowledge about specific locations of AGEs...
8.
Dar H, Perrien D, Pal S, Stoica A, Uppuganti S, Nyman J, et al.
J Clin Invest
. 2023 Mar;
133(8).
PMID: 36881482
IL-17A (IL-17), a driver of the inflammatory phase of fracture repair, is produced locally by several cell lineages including γδ T cells and Th17 cells. However, the origin of these...
9.
Unal M, Uppuganti S, Dapaah D, Ahmed R, Pennings J, Willett T, et al.
J Mech Behav Biomed Mater
. 2023 Feb;
140:105731.
PMID: 36827936
Raman spectroscopy (RS) is sensitive to the accumulation of advanced glycation end-products (AGEs), and it measures matrix-sensitive properties that correlate with the fracture toughness of human cortical bone. However, it...
10.
Ketsiri T, Uppuganti S, Harkins K, Gochberg D, Nyman J, Does M
NMR Biomed
. 2022 Nov;
36(5):e4878.
PMID: 36418236
MRI measures of bound and/or pore water concentration in cortical bone offer potential diagnostics of bone fracture risk. The transverse relaxation characteristics of both bound and pore water are relatively...