Mathilde Granke
Overview
Explore the profile of Mathilde Granke including associated specialties, affiliations and a list of published articles.
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22
Citations
541
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Recent Articles
1.
Creecy A, Uppuganti S, Girard M, Schlunk S, Amah C, Granke M, et al.
Bone
. 2019 Nov;
130:115126.
PMID: 31678497
One possibility for the disproportionate increase in fracture risk with aging relative to the decrease in bone mass is an accumulation of changes to the bone matrix which deleteriously affect...
2.
Nyman J, Uppuganti S, Unal M, Leverant C, Adabala S, Granke M, et al.
JBMR Plus
. 2019 Jul;
3(6):e10135.
PMID: 31346566
Being predictors of the mechanical properties of human cortical bone, bound and pore water measurements by magnetic resonance (MR) imaging are being developed for the clinical assessment of fracture risk....
3.
Willett T, Dapaah D, Uppuganti S, Granke M, Nyman J
Bone
. 2018 Nov;
120:187-193.
PMID: 30394355
Greater understanding of the determinants of skeletal fragility is highly sought due to the great burden that bone affecting diseases and fractures have on economies, societies and health care systems....
4.
Unal M, Uppuganti S, Leverant C, Creecy A, Granke M, Voziyan P, et al.
J Biophotonics
. 2018 Mar;
11(8):e201700352.
PMID: 29575566
Establishing a non-destructive method for spatially assessing advanced glycation end-products (AGEs) is a potentially useful step toward investigating the mechanistic role of AGEs in bone quality. To test the hypothesis...
5.
Makowski A, Granke M, Ayala O, Uppuganti S, Mahadevan-Jansen A, Nyman J
Appl Spectrosc
. 2017 Jul;
71(10):2385-2394.
PMID: 28708001
A decline in the inherent quality of bone tissue is a † Equal contributors contributor to the age-related increase in fracture risk. Although this is well-known, the important biochemical factors...
6.
Uppuganti S, Granke M, Manhard M, Does M, Perrien D, Lee D, et al.
J Orthop Res
. 2016 Aug;
35(7):1442-1452.
PMID: 27513922
Unlike the known relationships between traditional mechanical properties and microstructural features of bone, the factors that influence the mechanical resistance of bone to cyclic reference point microindention (cRPI) and impact...
7.
Granke M, Makowski A, Uppuganti S, Nyman J
J Biomech
. 2016 Jun;
49(13):2748-2755.
PMID: 27344202
Changes in the distribution of bone mineralization occurring with aging, disease, or treatment have prompted concerns that alterations in mineralization heterogeneity may affect the fracture resistance of bone. Yet, so...
8.
Nyman J, Granke M, Singleton R, Pharr G
Curr Osteoporos Rep
. 2016 Jun;
14(4):138-50.
PMID: 27263108
Tissue-level mechanical properties characterize mechanical behavior independently of microscopic porosity. Specifically, quasi-static nanoindentation provides measurements of modulus (stiffness) and hardness (resistance to yielding) of tissue at the length scale of...
9.
Creecy A, Uppuganti S, Merkel A, ONeal D, Makowski A, Granke M, et al.
Calcif Tissue Int
. 2016 May;
99(3):289-301.
PMID: 27209312
Individuals with type 2 diabetes (T2D) have a higher fracture risk compared to non-diabetics, even though their areal bone mineral density is normal to high. Identifying the mechanisms whereby diabetes...
10.
Manhard M, Uppuganti S, Granke M, Gochberg D, Nyman J, Does M
Bone
. 2016 Mar;
87:1-10.
PMID: 26993059
Accurately predicting fracture risk in the clinic is challenging because the determinants are multi-factorial. A common approach to fracture risk assessment is to combine X-ray-based imaging methods such as dual-energy...