Sara J C Gosline
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Explore the profile of Sara J C Gosline including associated specialties, affiliations and a list of published articles.
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33
Citations
729
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Recent Articles
11.
Larsson A, Bhatia H, Calizo A, Pollard K, Zhang X, Conniff E, et al.
Neuro Oncol
. 2023 May;
25(11):2044-2057.
PMID: 37246765
Background: Malignant peripheral nerve sheath tumors (MPNST) are aggressive soft tissue sarcomas that often develop in patients with neurofibromatosis type 1 (NF1). To address the critical need for novel therapeutics...
12.
Gosline S, Kim D, Pande P, Thomas D, Truong L, Hoffman P, et al.
Sci Data
. 2023 Mar;
10(1):151.
PMID: 36944655
The OSU/PNNL Superfund Research Program (SRP) represents a longstanding collaboration to quantify Polycyclic Aromatic Hydrocarbons (PAHs) at various superfund sites in the Pacific Northwest and assess their potential impact on...
13.
Gosline S, Tognon C, Nestor M, Joshi S, Modak R, Damnernsawad A, et al.
Clin Proteomics
. 2022 Jul;
19(1):30.
PMID: 35896960
Acute Myeloid Leukemia (AML) affects 20,000 patients in the US annually with a five-year survival rate of approximately 25%. One reason for the low survival rate is the high prevalence...
14.
Way G, Greene C, Carninci P, Carvalho B, de Hoon M, Finley S, et al.
PLoS Biol
. 2021 Oct;
19(10):e3001419.
PMID: 34618807
Evolving in sync with the computation revolution over the past 30 years, computational biology has emerged as a mature scientific field. While the field has made major contributions toward improving...
15.
Joshi S, Nechiporuk T, Bottomly D, Piehowski P, Reisz J, Pittsenbarger J, et al.
Cancer Cell
. 2021 Jun;
39(7):999-1014.e8.
PMID: 34171263
Our study details the stepwise evolution of gilteritinib resistance in FLT3-mutated acute myeloid leukemia (AML). Early resistance is mediated by the bone marrow microenvironment, which protects residual leukemia cells. Over...
16.
Danna V, Mitchell H, Anderson L, Godinez I, Gosline S, Teeguarden J, et al.
J Proteome Res
. 2021 Mar;
20(4):2116-2121.
PMID: 33703901
A generalized goal of many high-throughput data studies is to identify functional mechanisms that underlie observed biological phenomena, whether they be disease outcomes or metabolic output. Increasingly, studies that rely...
17.
Liu X, Gosline S, Pflieger L, Wallet P, Iyer A, Guinney J, et al.
Brief Bioinform
. 2021 Mar;
22(5).
PMID: 33681983
Single-cell RNA sequencing (scRNA-Seq) is an emerging strategy for characterizing immune cell populations. Compared to flow or mass cytometry, scRNA-Seq could potentially identify cell types and activation states that lack...
18.
Pollard K, Banerjee J, Doan X, Wang J, Guo X, Allaway R, et al.
Sci Data
. 2020 Jun;
7(1):184.
PMID: 32561749
Nerve sheath tumors occur as a heterogeneous group of neoplasms in patients with neurofibromatosis type 1 (NF1). The malignant form represents the most common cause of death in people with...
19.
Allaway R, La Rosa S, Verma S, Mangravite L, Guinney J, Blakeley J, et al.
Sci Data
. 2019 Dec;
6(1):319.
PMID: 31836719
No abstract available.
20.
Rice F, Houk G, Wymer J, Gosline S, Guinney J, Wu J, et al.
PLoS One
. 2019 May;
14(5):e0216527.
PMID: 31107888
In addition to large plexiform neurofibromas (pNF), NF1 patients are frequently disfigured by cutaneous neurofibromas (cNF) and are often afflicted with chronic pain and itch even from seemingly normal skin...