Paul D Piehowski
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Explore the profile of Paul D Piehowski including associated specialties, affiliations and a list of published articles.
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76
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1814
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Recent Articles
1.
Velickovic M, Kadam L, Kim J, Zemaitis K, Velickovic D, Gao Y, et al.
Nat Commun
. 2025 Feb;
16(1):2061.
PMID: 40021619
The placenta is a complex and heterogeneous organ that links the mother and fetus, playing a crucial role in nourishing and protecting the fetus throughout pregnancy. Integrative spatial multi-omics approaches...
2.
Allen B, Bottomly D, Kohnke T, Wang A, Lin H, Johnson K, et al.
Blood
. 2025 Feb;
PMID: 40009487
MDM2 inhibitors are promising therapeutics for acute myeloid leukemia (AML) with wild-type TP53. Through an integrated analysis of functional genomic data from primary patient samples, we found that an MDM2...
3.
Joshi S, Huang A, Pittsenbarger J, Shinde U, Posso C, Piehowski P, et al.
Haematologica
. 2025 Feb;
PMID: 39945005
Not available.
4.
Pino M, Dijkstra P, Whytock K, Ahn C, Yu G, Sanford J, et al.
Am J Physiol Endocrinol Metab
. 2025 Feb;
328(3):E478-E492.
PMID: 39933702
White adipose tissue (WAT) plays a significant role in whole body energy homeostasis, and its excess typifies obesity. In addition to WAT quantity, perturbations in the basic cellular processes of...
5.
Kitata R, Velickovic M, Xu Z, Zhao R, Scholten D, Chu R, et al.
Nat Commun
. 2025 Jan;
16(1):547.
PMID: 39805815
With advanced mass spectrometry (MS)-based proteomics, genome-scale proteome coverage can be achieved from bulk tissues. However, such bulk measurement lacks spatial resolution and obscures tissue heterogeneity, precluding proteome mapping of...
6.
Swensen A, Piehowski P, Chen J, Chan X, Kelly S, Petyuk V, et al.
bioRxiv
. 2024 Sep;
PMID: 39345556
Aims/hypothesis: Progression to type 1 diabetes (T1D) is associated with genetic factors, the presence of autoantibodies, and a decline in β cell insulin secretion in response to glucose. Very little...
7.
Velickovic M, Fillmore T, Attah I, Posso C, Pino J, Zhao R, et al.
Anal Chem
. 2024 Aug;
96(32):12973-12982.
PMID: 39089681
There is increasing interest in developing in-depth proteomic approaches for mapping tissue heterogeneity in a cell-type-specific manner to better understand and predict the function of complex biological systems such as...
8.
Jakicic J, Kohrt W, Houmard J, Miller M, Radom-Aizik S, Rasmussen B, et al.
J Appl Physiol (1985)
. 2024 Apr;
137(3):473-493.
PMID: 38634503
Physical activity, including structured exercise, is associated with favorable health-related chronic disease outcomes. Although there is evidence of various molecular pathways that affect these responses, a comprehensive molecular map of...
9.
Velickovic M, Wu R, Gao Y, Thairu M, Velickovic D, Munoz N, et al.
Nat Chem Biol
. 2024 Feb;
20(8):1033-1043.
PMID: 38302607
The leaf-cutter ant fungal garden ecosystem is a naturally evolved model system for efficient plant biomass degradation. Degradation processes mediated by the symbiotic fungus Leucoagaricus gongylophorus are difficult to characterize...
10.
Pino J, Posso C, Joshi S, Nestor M, Moon J, Hansen J, et al.
Cell Rep Med
. 2024 Jan;
5(1):101359.
PMID: 38232702
Acute myeloid leukemia is a poor-prognosis cancer commonly stratified by genetic aberrations, but these mutations are often heterogeneous and fail to consistently predict therapeutic response. Here, we combine transcriptomic, proteomic,...