Sandrine Silvente-Poirot
Overview
Explore the profile of Sandrine Silvente-Poirot including associated specialties, affiliations and a list of published articles.
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71
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6274
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Recent Articles
1.
de Medina P, Ayadi S, Diallo K, Bunay J, Pucheu L, Soules R, et al.
Adv Exp Med Biol
. 2023 Nov;
1440:149-161.
PMID: 38036879
Cholesterol-5,6-epoxides (5,6-ECs) are oxysterols (OS) that have been linked to several pathologies including cancers and neurodegenerative diseases. 5,6-ECs can be produced from cholesterol by several mechanisms including reactive oxygen species,...
2.
Ayadi S, Friedrichs S, Soules R, Pucheu L, Lutjohann D, Silvente-Poirot S, et al.
J Lipid Res
. 2023 Nov;
64(12):100479.
PMID: 37981011
Oncosterone (6-oxo-cholestane-3β,5α-diol; OCDO) is an oncometabolite and a tumor promoter on estrogen receptor alpha-positive breast cancer (ER(+) BC) and triple-negative breast cancers (TN BC). OCDO is an oxysterol formed in...
3.
de Medina P, Ayadi S, Soules R, Payre B, Rup-Jacques S, Silvente-Poirot S, et al.
J Steroid Biochem Mol Biol
. 2023 Sep;
234:106396.
PMID: 37683773
Cholestane-3β,5α,6β-triol (CT) is a primary metabolite of 5,6-epoxycholesterols (5,6-EC) that is catalyzed by the cholesterol-5,6-epoxide hydrolase (ChEH). CT is a well-known biomarker for Niemann-Pick disease type C (NP-C), a progressive...
4.
Hassen C, Goupille C, Vigor C, Durand T, Gueraud F, Silvente-Poirot S, et al.
J Steroid Biochem Mol Biol
. 2023 Jun;
232:106346.
PMID: 37321513
Cholesterol plays important roles in many physiological processes, including cell membrane structure and function, hormone synthesis, and the regulation of cellular homeostasis. The role of cholesterol in breast cancer is...
5.
Khallouki F, Hajji L, Saber S, Bouddine T, Edderkaoui M, Bourhia M, et al.
J Pers Med
. 2023 May;
13(5).
PMID: 37240924
Breast cancer (BC) is the most common female cancer in terms of incidence and mortality worldwide. Tamoxifen (Nolvadex) is a widely prescribed, oral anti-estrogen drug for the hormonal treatment of...
6.
de Medina P, Bunay J, Poirot M, Record M, Silvente-Poirot S
Autophagy
. 2022 Sep;
19(3):1036-1038.
PMID: 36063487
Normal cells secrete small extracellular vesicles (sEV), containing exosomes and/or ectosomes, which play a beneficial role in monitoring tissue integrity and immune response, whereas cancer cells constitutively secrete sEV, which...
7.
Record M, Attia M, Carayon K, Pucheu L, Bunay J, Soules R, et al.
J Extracell Vesicles
. 2022 Apr;
11(4):e12211.
PMID: 35411723
Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes. Dendrogenin A (DDA) is an...
8.
de Medina P, Silvente-Poirot S, Poirot M
Ageing Res Rev
. 2022 Mar;
77:101615.
PMID: 35351610
Delaying and even reversing ageing is a major public health challenge with a tremendous potential to postpone a plethora of diseases including cancer, metabolic syndromes and neurodegenerative disorders. A better...
9.
Montfort A, Bertrand F, Rochotte J, Gilhodes J, Filleron T, Milhes J, et al.
Cancer Immunol Res
. 2021 Mar;
9(5):568-582.
PMID: 33727246
Dysregulation of lipid metabolism affects the behavior of cancer cells, but how this happens is not completely understood. Neutral sphingomyelinase 2 (nSMase2), encoded by , catalyzes the breakdown of sphingomyelin...
10.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...