Michel Record
Overview
Explore the profile of Michel Record including associated specialties, affiliations and a list of published articles.
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34
Citations
2961
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Recent Articles
1.
de Medina P, Ayadi S, Diallo K, Bunay J, Pucheu L, Soules R, et al.
Adv Exp Med Biol
. 2023 Nov;
1440:149-161.
PMID: 38036879
Cholesterol-5,6-epoxides (5,6-ECs) are oxysterols (OS) that have been linked to several pathologies including cancers and neurodegenerative diseases. 5,6-ECs can be produced from cholesterol by several mechanisms including reactive oxygen species,...
2.
de Medina P, Bunay J, Poirot M, Record M, Silvente-Poirot S
Autophagy
. 2022 Sep;
19(3):1036-1038.
PMID: 36063487
Normal cells secrete small extracellular vesicles (sEV), containing exosomes and/or ectosomes, which play a beneficial role in monitoring tissue integrity and immune response, whereas cancer cells constitutively secrete sEV, which...
3.
Record M, Attia M, Carayon K, Pucheu L, Bunay J, Soules R, et al.
J Extracell Vesicles
. 2022 Apr;
11(4):e12211.
PMID: 35411723
Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes. Dendrogenin A (DDA) is an...
4.
Montfort A, Bertrand F, Rochotte J, Gilhodes J, Filleron T, Milhes J, et al.
Cancer Immunol Res
. 2021 Mar;
9(5):568-582.
PMID: 33727246
Dysregulation of lipid metabolism affects the behavior of cancer cells, but how this happens is not completely understood. Neutral sphingomyelinase 2 (nSMase2), encoded by , catalyzes the breakdown of sphingomyelin...
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6.
Serhan N, Mouchel P, de Medina P, Segala G, Mougel A, Saland E, et al.
Cancers (Basel)
. 2020 Jul;
12(7).
PMID: 32610562
Dendrogenin A (DDA) is a mammalian cholesterol metabolite that displays potent antitumor properties on acute myeloid leukemia (AML). DDA triggers lethal autophagy in cancer cells through a biased activation of...
7.
Carriere F, Longhi S, Record M
Biochimie
. 2020 Jun;
179:237-246.
PMID: 32485205
The anti-malarial drug Chloroquine (CQ) and its derivative hydroxychloroquine have shown antiviral activities in vitro against many viruses, including coronaviruses, dengue virus and the biosafety level 4 Nipah and Hendra...
8.
Record M, Silvente-Poirot S, Poirot M, Wakelam M
J Lipid Res
. 2018 May;
59(8):1316-1324.
PMID: 29764923
Intercellular communication has been known for decades to involve either direct contact between cells or to operate via circulating molecules, such as cytokines, growth factors, or lipid mediators. During the...
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10.
Segala G, David M, de Medina P, Poirot M, Serhan N, Vergez F, et al.
Nat Commun
. 2017 Dec;
8(1):1903.
PMID: 29199269
Dendrogenin A (DDA) is a newly discovered cholesterol metabolite with tumor suppressor properties. Here, we explored its efficacy and mechanism of cell death in melanoma and acute myeloid leukemia (AML)....