Samuel W Cushman
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Explore the profile of Samuel W Cushman including associated specialties, affiliations and a list of published articles.
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51
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2484
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Recent Articles
1.
Hansson B, Wasserstrom S, Moren B, Periwal V, Vikman P, Cushman S, et al.
J Mol Endocrinol
. 2018 Jan;
60(3):199-211.
PMID: 29339400
To capture immediate cellular changes during diet-induced expansion of adipocyte cell volume and number, we characterized mature adipocytes during a short-term high-fat diet (HFD) intervention. Male C57BL6/J mice were fed...
2.
Marcondes R, Maliqueo M, Fornes R, Benrick A, Hu M, Ivarsson N, et al.
Mol Cell Endocrinol
. 2017 Mar;
448:66-76.
PMID: 28344042
Here we hypothesized that exercise in dihydrotestosterone (DHT) or letrozole (LET)-induced polycystic ovary syndrome mouse models improves impaired insulin and glucose metabolism, adipose tissue morphology, and expression of genes related...
3.
Liu L, Craig C, Tolentino L, Choi O, Morton J, Rivas H, et al.
PLoS One
. 2017 Feb;
12(2):e0170728.
PMID: 28151993
Aim: The physiologic mechanisms underlying the relationship between obesity and insulin resistance are not fully understood. Impaired adipocyte differentiation and localized inflammation characterize adipose tissue from obese, insulin-resistant humans. The...
4.
Bennet L, Stenkula K, Cushman S, Brismar K
BMC Public Health
. 2016 Dec;
16(1):1242.
PMID: 27938404
Background: The aim of this study was to identify corresponding body mass index (BMI) and waist circumference cut-offs for equivalent levels of insulin sensitivity in a Middle Eastern immigrant population...
5.
Domingo-Espin J, Lindahl M, Nilsson-Wolanin O, Cushman S, Stenkula K, Lagerstedt J
Diabetes
. 2016 May;
65(7):1838-48.
PMID: 27207515
Apolipoprotein A-I (apoA-I) of HDL is central to the transport of cholesterol in circulation. ApoA-I also provides glucose control with described in vitro effects of apoA-I on β-cell insulin secretion...
6.
Li Y, Periwal V, Cushman S, Stenkula K
Adipocyte
. 2016 May;
5(1):81-7.
PMID: 27144099
Adipose tissue is the energy buffer in mammals. The cellularity of adipose tissue has a major role in determining the response of adipose tissue to insulin action. A reduction in...
7.
McLaughlin T, Craig C, Liu L, Perelman D, Allister C, Spielman D, et al.
Diabetes
. 2016 Feb;
65(5):1245-54.
PMID: 26884438
Obesity is associated with insulin resistance, but significant variability exists between similarly obese individuals, pointing to qualitative characteristics of body fat as potential mediators. To test the hypothesis that obese,...
8.
Eliasson B, Smith U, Mullen S, Cushman S, Sherman A, Yang J
Adipocyte
. 2015 Aug;
3(4):314-21.
PMID: 26317056
Early studies reported that the size of adipose cells positively correlates with insulin resistance, but recent evidence suggests that the relationship between adipose cell size and insulin resistance is more...
9.
Lizunov V, Stenkula K, Blank P, Troy A, Lee J, Skarulis M, et al.
PLoS One
. 2015 Mar;
10(3):e0119291.
PMID: 25768970
While intercellular communication processes are frequently characterized by switch-like transitions, the endocrine system, including the adipose tissue response to insulin, has been characterized by graded responses. Yet here individual cells...
10.
Allister C, Liu L, Lamendola C, Craig C, Cushman S, Hellerstein M, et al.
J Lipid Res
. 2014 Nov;
56(2):435-9.
PMID: 25418322
Indirect evidence suggests that impaired triglyceride storage in the subcutaneous fat depot contributes to the development of insulin resistance via lipotoxicity. We directly tested this hypothesis by measuring, in vivo,...