Samuel W Cushman
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Explore the profile of Samuel W Cushman including associated specialties, affiliations and a list of published articles.
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51
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2484
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Recent Articles
11.
Stenkula K, Lindahl M, Petrlova J, Dalla-Riva J, Goransson O, Cushman S, et al.
Diabetologia
. 2014 Jan;
57(4):797-800.
PMID: 24442447
Aims/hypothesis: Apolipoprotein A-I (apoA-I), the main protein constituent of HDL, has a central role in the reverse cholesterol-transport pathway, which together with the anti-inflammatory properties of apoA-I/HDL provide cardioprotection. Recent...
12.
Crivat G, Lizunov V, Li C, Stenkula K, Zimmerberg J, Cushman S, et al.
PLoS One
. 2013 Nov;
8(11):e77953.
PMID: 24223128
The fruit fly Drosophila melanogaster is an excellent model system for studies of genes controlling development and disease. However, its applicability to physiological systems is less clear because of metabolic...
13.
Guo H, Bazuine M, Jin D, Huang M, Cushman S, Chen X
Endocrinology
. 2013 Jul;
154(10):3525-38.
PMID: 23885013
Lipocalin 2 (Lcn2) has previously been characterized as an adipokine/cytokine playing a role in glucose and lipid homeostasis. In this study, we investigate the role of Lcn2 in adipose tissue...
14.
Lizunov V, Lee J, Skarulis M, Zimmerberg J, Cushman S, Stenkula K
Diabetes
. 2013 Jun;
62(9):3114-9.
PMID: 23801575
Systemic glucose homeostasis is profoundly influenced by adipose cell function. Here we investigated GLUT4 dynamics in living adipose cells from human subjects with varying BMI and insulin sensitivity index (Si)...
15.
Lizunov V, Stenkula K, Troy A, Cushman S, Zimmerberg J
PLoS One
. 2013 Mar;
8(3):e57559.
PMID: 23520472
Insulin-stimulated delivery of glucose transporter-4 (GLUT4) to the plasma membrane (PM) is the hallmark of glucose metabolism. In this study we examined insulin's effects on GLUT4 organization in PM of...
16.
Kursawe R, Caprio S, Giannini C, Narayan D, Lin A, DAdamo E, et al.
Diabetes
. 2012 Dec;
62(3):837-44.
PMID: 23209190
Insulin resistance associated with altered fat partitioning in liver and adipose tissues is a prediabetic condition in obese adolescents. We investigated interactions between glucose tolerance, insulin sensitivity, and the expression...
17.
Lizunov V, Stenkula K, Lisinski I, Gavrilova O, Yver D, Chadt A, et al.
Am J Physiol Endocrinol Metab
. 2012 Feb;
302(8):E950-60.
PMID: 22297303
Insulin regulates glucose uptake into fat and muscle by modulating the subcellular distribution of GLUT4 between the cell surface and intracellular compartments. However, quantification of these translocation processes in muscle...
18.
Yang J, Eliasson B, Smith U, Cushman S, Sherman A
Obesity (Silver Spring)
. 2012 Jan;
20(5):932-8.
PMID: 22240722
Early studies reported that the size of adipose cells correlates with insulin resistance. However, a recent study comparing moderately obese, sensitive and resistant subjects, with comparable BMI (~30), did not...
19.
Teng R, Gavrilova O, Suzuki N, Chanturiya T, Schimel D, Hugendubler L, et al.
Nat Commun
. 2011 Nov;
2:520.
PMID: 22044999
Although erythropoietin (Epo) is the cytokine known to regulate erythropoiesis, erythropoietin receptor (EpoR) expression and associated activity beyond haematopoietic tissue remain uncertain. Here we show that mice with EpoR expression...
20.
Chen X, Hunt D, Cushman S, Hess S
Proteomics Clin Appl
. 2010 Dec;
3(9):1099-111.
PMID: 21137009
Signaling molecules released by adipose tissue have been implicated in inflammation, adipocyte dysfunction and systemic insulin resistance. In this study, we used 2-D LC-MS/MS and quantitative proteomics approaches to characterize...