Sameet Mehta
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Explore the profile of Sameet Mehta including associated specialties, affiliations and a list of published articles.
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37
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1238
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Recent Articles
11.
Tiegs A, Titus S, Mehta S, Garcia-Milian R, Seli E, Scott Jr R
Reprod Biomed Online
. 2021 Aug;
43(4):614-626.
PMID: 34417138
Research Question: Can cumulus cells be used as a non-invasive target for the study of determinants of preimplantation embryo quality? Design: Cumulus cells were collected from monosomy 21, trisomy 21...
12.
Spronck B, Latorre M, Wang M, Mehta S, Caulk A, Ren P, et al.
J R Soc Interface
. 2021 Jul;
18(180):20210336.
PMID: 34314650
Hypertension induces significant aortic remodelling, often adaptive but sometimes not. To identify immuno-mechanical mechanisms responsible for differential remodelling, we studied thoracic aortas from 129S6/SvEvTac and C57BL/6 J mice before and...
13.
Kurokawa C, Narasimhan S, Vidyarthi A, Booth C, Mehta S, Meister L, et al.
Ticks Tick Borne Dis
. 2020 Sep;
11(6):101529.
PMID: 32993942
Ticks deposit salivary proteins into the skin during a bite to mediate acquisition of a blood meal. Acquired resistance to tick bites has been demonstrated to prevent Borrelia burgdorferi sensu...
14.
Liu R, Yeh Y, Varabyou A, Collora J, Sherrill-Mix S, Talbot Jr C, et al.
Sci Transl Med
. 2020 May;
12(543).
PMID: 32404504
Understanding HIV-1-host interactions can identify the cellular environment supporting HIV-1 reactivation and mechanisms of clonal expansion. We developed HIV-1 SortSeq to isolate rare HIV-1-infected cells from virally suppressed, HIV-1-infected individuals...
15.
Zhou H, Mehta S, Srivastava S, Grabinska K, Zhang X, Wong C, et al.
JCI Insight
. 2020 Feb;
5(3).
PMID: 32051336
Vascular inflammation is present in many cardiovascular diseases, and exogenous glucocorticoids have traditionally been used as a therapy to suppress inflammation. However, recent data have shown that endogenous glucocorticoids, acting...
16.
Li G, Wang M, Caulk A, Cilfone N, Gujja S, Qin L, et al.
J Clin Invest
. 2020 Feb;
130(3):1233-1251.
PMID: 32039915
Smooth muscle cell (SMC) proliferation has been thought to limit the progression of thoracic aortic aneurysm and dissection (TAAD) because loss of medial cells associates with advanced disease. We investigated...
17.
Premi S, Han L, Mehta S, Knight J, Zhao D, Palmatier M, et al.
Proc Natl Acad Sci U S A
. 2019 Nov;
116(48):24196-24205.
PMID: 31723047
If the genome contains outlier sequences extraordinarily sensitive to environmental agents, these would be sentinels for monitoring personal carcinogen exposure and might drive direct changes in cell physiology rather than...
18.
Girgenti M, Wohleb E, Mehta S, Ghosal S, Fogaca M, Duman R
Transl Psychiatry
. 2019 Nov;
9(1):292.
PMID: 31712551
γ-aminobutyric acid (GABA) inhibitory interneurons play a key role in efferent and afferent control of principle neuron activity in the prefrontal cortex (PFC), thereby regulating signal integrity of cognitive and...
19.
Sahraei M, Chaube B, Liu Y, Sun J, Kaplan A, Price N, et al.
J Clin Invest
. 2019 Nov;
129(12):5518-5536.
PMID: 31710308
microRNA-21 (miR-21) is the most commonly upregulated miRNA in solid tumors. This cancer-associated microRNA (oncomiR) regulates various downstream effectors associated with tumor pathogenesis during all stages of carcinogenesis. In this...
20.
Chiu J, Thekkiniath J, Mehta S, Muller C, Bracher F, Ben Mamoun C
J Biol Chem
. 2019 Aug;
294(40):14757-14767.
PMID: 31409644
In fungi, ergosterol is an essential component of the plasma membrane. Its biosynthesis from acetyl-CoA is the primary target of the most commonly used antifungal drugs. Here, we show that...