Saeed Saberi
Overview
Explore the profile of Saeed Saberi including associated specialties, affiliations and a list of published articles.
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14
Citations
879
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0
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Recent Articles
1.
Takata K, Chong L, Ennishi D, Aoki T, Li M, Thakur A, et al.
J Clin Invest
. 2022 Apr;
132(10).
PMID: 35380993
PRAME is a prominent member of the cancer testis antigen family of proteins, which triggers autologous T cell-mediated immune responses. Integrative genomic analysis in diffuse large B cell lymphoma (DLBCL)...
2.
Ennishi D, Healy S, Bashashati A, Saberi S, Hother C, Mottok A, et al.
Nat Med
. 2020 Feb;
26(4):577-588.
PMID: 32094924
Transmembrane protein 30A (TMEM30A) maintains the asymmetric distribution of phosphatidylserine, an integral component of the cell membrane and 'eat-me' signal recognized by macrophages. Integrative genomic and transcriptomic analysis of diffuse...
3.
Aoki T, Chong L, Takata K, Milne K, Hav M, Colombo A, et al.
Cancer Discov
. 2019 Dec;
10(3):406-421.
PMID: 31857391
Hodgkin lymphoma is characterized by an extensively dominant tumor microenvironment (TME) composed of different types of noncancerous immune cells with rare malignant cells. Characterization of the cellular components and their...
4.
Chafe S, McDonald P, Saberi S, Nemirovsky O, Venkateswaran G, Burugu S, et al.
Cancer Immunol Res
. 2019 May;
7(7):1064-1078.
PMID: 31088846
Treatment strategies involving immune-checkpoint blockade (ICB) have significantly improved survival for a subset of patients across a broad spectrum of advanced solid cancers. Despite this, considerable room for improving response...
5.
McDonald P, Chafe S, Brown W, Saberi S, Swayampakula M, Venkateswaran G, et al.
Gastroenterology
. 2019 May;
157(3):823-837.
PMID: 31078621
Background & Aims: Most pancreatic ductal adenocarcinomas (PDACs) express an activated form of KRAS, become hypoxic and dysplastic, and are refractory to chemo and radiation therapies. To survive in the...
6.
Ennishi D, Takata K, Beguelin W, Duns G, Mottok A, Farinha P, et al.
Cancer Discov
. 2019 Feb;
9(4):546-563.
PMID: 30705065
We performed a genomic, transcriptomic, and immunophenotypic study of 347 patients with diffuse large B-cell lymphoma (DLBCL) to uncover the molecular basis underlying acquired deficiency of MHC expression. Low MHC-II...
7.
Ennishi D, Jiang A, Boyle M, Collinge B, Grande B, Ben-Neriah S, et al.
J Clin Oncol
. 2018 Dec;
37(3):190-201.
PMID: 30523716
Purpose: High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH) has a poor outcome after standard chemoimmunotherapy. We sought to understand the biologic underpinnings of HGBL-DH/TH with BCL2...
8.
Ennishi D, Mottok A, Ben-Neriah S, Shulha H, Farinha P, Chan F, et al.
Blood
. 2017 Mar;
129(20):2760-2770.
PMID: 28351934
The clinical significance of and genetic alterations in diffuse large B-cell lymphoma (DLBCL), apart from translocations, has not been comprehensively investigated using high-resolution genetic assays. In this study, we profiled...
9.
Chun H, Lim E, Heravi-Moussavi A, Saberi S, Mungall K, Bilenky M, et al.
Cancer Cell
. 2016 Mar;
29(3):394-406.
PMID: 26977886
Malignant rhabdoid tumors (MRTs) are rare lethal tumors of childhood that most commonly occur in the kidney and brain. MRTs are driven by SMARCB1 loss, but the molecular consequences of...
10.
Pon J, Wong J, Saberi S, Alder O, Moksa M, Cheng S, et al.
Nat Commun
. 2015 Aug;
6:7953.
PMID: 26245647
Myocyte enhancer factor 2B (MEF2B) is a transcription factor with mutation hotspots at K4, Y69 and D83 in diffuse large B-cell lymphoma (DLBCL). To provide insight into the regulatory network...