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S P Soltoff

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Articles 56
Citations 1666
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Recent Articles
1.
Benes C, Poulogiannis G, Cantley L, Soltoff S
Oncogene . 2011 Jul; 31(5):653-63. PMID: 21725358
Multiple SRC-family kinases (SFKs) are commonly activated in carcinoma and appear to have a role in metastasis through incompletely understood mechanisms. Recent studies have shown that CDCP1 (CUB (complement C1r/C1s,...
2.
Godwin S, Soltoff S
Bone . 2002 Apr; 30(4):559-66. PMID: 11934646
Elevated extracellular calcium (Ca(e)) stimulates both chemotaxis and mitogenesis of MC3T3-E1 osteoblasts via a calcium-sensing receptor (CasR). Ca(e)-mediated chemotaxis of these bone-forming cells is dependent on phospholipase C (PLC) and...
3.
Singh V, Saluja A, Bhagat L, van Acker G, Song A, Soltoff S, et al.
J Clin Invest . 2001 Nov; 108(9):1387-95. PMID: 11696584
Intra-acinar cell activation of digestive enzyme zymogens including trypsinogen is generally believed to be an early and critical event in acute pancreatitis. We have found that the phosphatidylinositol 3-kinase inhibitor...
4.
Soltoff S
J Biol Chem . 2001 Aug; 276(41):37986-92. PMID: 11498535
Protein kinase Cdelta (PKCdelta) is activated by stimuli that increase its tyrosine phosphorylation, including neurotransmitters that initiate fluid secretion in salivary gland (parotid) epithelial cells. Rottlerin, a compound reported to...
5.
Benes C, Soltoff S
Am J Physiol Cell Physiol . 2001 May; 280(6):C1498-510. PMID: 11350745
Protein kinase C (PKC) delta becomes tyrosine phosphorylated in rat parotid acinar cells exposed to muscarinic and substance P receptor agonists, which initiate fluid secretion in this salivary cell. Here...
6.
Warny M, Aboudola S, Robson S, Sevigny J, Communi D, Soltoff S, et al.
J Biol Chem . 2001 May; 276(28):26051-6. PMID: 11349132
Extracellular nucleotides are autocrine and paracrine cellular mediators that signal through P2 nucleotide receptors. Monocytic cells express several P2Y receptors but the role of these G protein-coupled receptors in monocytes...
7.
Benes C, Zheng Y, Soltoff S
J Korean Med Sci . 2000 Sep; 15 Suppl:S40-1. PMID: 10981509
Receptor- and nonreceptor-mediated stimuli produce increases in both PKCdelta tyrosine phosphorylation and activity in rat parotid acinar cells and other cells. In vivo and in vitro increases and decreases in...
8.
Zhang Z, Yang X, Soltoff S, Cohen D
Am J Physiol Renal Physiol . 2000 Feb; 278(1):F155-64. PMID: 10644667
Growth factors and other stimuli increase the activity of phosphatidylinositol-3 kinase (PI3K), an SH2 domain-containing lipid kinase. In the murine kidney inner medullary mIMCD3 cell line, urea (200 mM) increased...
9.
DeMali K, Godwin S, Soltoff S, Kazlauskas A
Exp Cell Res . 1999 Dec; 253(1):271-9. PMID: 10579928
The observation that platelet-derived growth factor (PDGF) increases the catalytic activity of Src family members (Src) suggests that they contribute to PDGF-dependent responses. The role of Src in PDGF-dependent cell...
10.
Bradford M, Soltoff S
Eur J Morphol . 1998 Nov; 36 Suppl:176-80. PMID: 9825917
The aim of these studies was to examine the involvement of tyrosine phosphorylation in the signal transduction pathways and secretory events that are promoted by receptor agonists acting on rat...