S P Kunapuli
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Explore the profile of S P Kunapuli including associated specialties, affiliations and a list of published articles.
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79
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1298
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Recent Articles
21.
Quinton T, Murugappan S, Kim S, Jin J, Kunapuli S
J Thromb Haemost
. 2004 May;
2(6):978-84.
PMID: 15140134
Alpha granule release plays an important role in propagating a hemostatic response upon platelet activation. We evaluated the ability of various agonists to cause alpha granule release in platelets. Alpha...
22.
Dorsam R, Tuluc M, Kunapuli S
J Thromb Haemost
. 2004 Apr;
2(5):804-12.
PMID: 15099288
The activated platelet surface serves as an integral part of the prothrombinase complex upon activation by potent platelet agonists such as thrombin and collagen. We determined the receptor specificity through...
23.
Paul B, Vilaire G, Kunapuli S, Bennett J
J Thromb Haemost
. 2003 Jul;
1(4):814-20.
PMID: 12871420
The integrin alphavbeta3 mediates platelet adhesion to the matrix protein osteopontin and likely is the predominant integrin mediating platelet adhesion to the matrix protein vitronectin. To address the mechanism that...
24.
Jin J, Tomlinson W, Kirk I, Kim Y, Humphries R, Kunapuli S
Br J Pharmacol
. 2001 Jun;
133(4):521-8.
PMID: 11399669
P2Y receptor activation in many cell types leads to phospholipase C activation and accumulation of inositol phosphates, while in blood platelets, C6-2B glioma cells, and in B10 microvascular endothelial cells...
25.
Ozdener F, Kunapuli S, Daniel J
Platelets
. 2001 Apr;
12(2):121-3.
PMID: 11297033
Phospholipase Cgamma2 (PLCgamma2), the predominant isoform of phospholipase C expressed in platelets, plays a major role in activation of platelets by collagen. Although PLCgamma2 has been shown to be tyrosine...
26.
Dangelmaier C, Jin J, Smith J, Kunapuli S
Thromb Haemost
. 2001 Mar;
85(2):341-8.
PMID: 11246558
Platelet activation results in shape change, aggregation, generation of thromboxane A2, and release of granule contents. We have recently demonstrated that secreted ADP is essential for thromboxane A2-induced platelet aggregation...
27.
Mao G, Kunapuli S, Rao A
Br J Haematol
. 2000 Sep;
110(2):402-8.
PMID: 10971398
Alternatively spliced forms have been reported for several phospholipase C (PLC) isozymes, but not for PLC-beta2, the most abundant PLC-beta in platelets. PLC-beta2 cDNA cloned from the HL-60-cell cDNA library...
28.
Dasari V, Jin J, Kunapuli S
Immunopharmacology
. 2000 Aug;
48(2):157-63.
PMID: 10936513
Leukotriene B4 (LTB4), a product of arachidonic acid metabolism, plays an important role in inflammatory responses. We have cloned from human erythroleukemia cells, a G protein-coupled receptor, designated P2Y(7), which...
29.
Dangelmaier C, Jin J, Daniel J, Smith J, Kunapuli S
Eur J Biochem
. 2000 Apr;
267(8):2283-9.
PMID: 10759852
U46619, a thromboxane A2 mimetic, but not ADP, caused activation of p38 mitogen activated protein (MAP) kinase in aspirin-treated platelets. In nonaspirinated human platelets ADP activated p38 MAP kinase in...
30.
Yung L, Lim F, Khan M, Kunapuli S, Rick L, Colman R, et al.
Biomaterials
. 2000 Feb;
21(4):405-14.
PMID: 10656323
Adsorbed proteins on biomaterial surfaces determine whether cells adhere, but rheological variables are also critical. Neutrophil adhesion under well-defined radial flow conditions was studied on glass preadsorbed with plasma proteins...