S P Kunapuli
Overview
Explore the profile of S P Kunapuli including associated specialties, affiliations and a list of published articles.
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79
Citations
1298
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Recent Articles
11.
Getz T, Dangelmaier C, Jin J, Daniel J, Kunapuli S
J Thromb Haemost
. 2010 Jul;
8(10):2283-93.
PMID: 20670370
Background: Myosin IIA is an essential platelet contractile protein that is regulated by phosphorylation of its regulatory light chain (MLC) on residues (Thr)18 and (Ser)19 via the myosin light chain...
12.
Quinter P, Dangelmaier C, Quinton T, Kunapuli S, Daniel J
J Thromb Haemost
. 2006 Nov;
5(2):362-8.
PMID: 17096705
Background: It has been reported that the association of glycoprotein VI (GPVI) with lipid rafts regulates GPVI signaling in platelets. Objective: Secreted adenosine 5'-diphosphate (ADP) potentiates GPVI-induced platelet aggregation at...
13.
Shankar H, Kahner B, Kunapuli S
Curr Drug Targets
. 2006 Nov;
7(10):1253-63.
PMID: 17073586
Platelet activation and aggregation is an integral component of the pathophysiology that leads to thrombotic and ischemic diseases such as cerebral stroke, peripheral vascular disease and myocardial infarction. Anti-platelet agents...
14.
Kahner B, Shankar H, Murugappan S, Prasad G, Kunapuli S
J Thromb Haemost
. 2006 Oct;
4(11):2317-26.
PMID: 17059469
Upon injury to a vessel wall the exposure of subendothelial collagen results in the activation of platelets. Platelet activation culminates in shape change, aggregation, release of granule contents and generation...
15.
Jalagadugula G, Dhanasekaran D, Kim S, Kunapuli S, Rao A
J Thromb Haemost
. 2006 Sep;
4(12):2678-86.
PMID: 16995904
Background: Galphaq (Gene GNAQ) plays a major role in platelet signal transduction but little is known regarding its transcriptional regulation. Objectives: We studied Galphaq promoter activity using luciferase reporter gene...
16.
Kim Y, Jin J, Dangelmaier C, Daniel J, Kunapuli S
Platelets
. 2006 Jun;
10(6):399-406.
PMID: 16801119
Adenosine diphosphate (ADP) is an important platelet agonist, causing the shape change and aggregation required for physiological hemostasis. We have recently demonstrated that the P2Y1 receptor plays an important role...
17.
18.
Bredetean O, Tuluc F, Ciochina A, Iacob G, Meshki J, Kunapuli S
Rev Med Chir Soc Med Nat Iasi
. 2006 Apr;
109(1):191-9.
PMID: 16607854
Nucleotides are important extracellular signaling molecules. It has been established that nucleotides are released from damaged cells, activated platelets and endothelial cells. Thus, at the site of vascular injury, the...
19.
Shankar H, Garcia A, Prabhakar J, Kim S, Kunapuli S
J Thromb Haemost
. 2006 Feb;
4(3):638-47.
PMID: 16460446
Background: Thromboxane A2 (TXA2) is a positive feedback lipid mediator that is generated upon stimulation of platelets with various agonists. Aspirin works as an antithrombotic drug by blocking the generation...
20.
Quinton T, Kim S, Jin J, Kunapuli S
J Thromb Haemost
. 2005 May;
3(5):1036-41.
PMID: 15869601
ADP is important in propagating hemostasis upon its secretion from activated platelets in response to other agonists. Lipid rafts are microdomains within the plasma membrane that are rich in cholesterol...