Ryan D Sheldon
Overview
Explore the profile of Ryan D Sheldon including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
57
Citations
1140
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ma S, Dahabieh M, Mann T, Zhao S, McDonald B, Song W, et al.
Science
. 2024 Dec;
387(6734):eadj3020.
PMID: 39666821
Exhausted T cells (TEX) in cancer and chronic viral infections undergo metabolic and epigenetic remodeling, impairing their protective capabilities. However, the impact of nutrient metabolism on epigenetic modifications that control...
2.
Oswald B, DeCamp L, Longo J, Dahabieh M, Bunda N, Ma S, et al.
bioRxiv
. 2024 Nov;
PMID: 39605550
Reducing calorie intake without malnutrition limits tumor progression but the underlying mechanisms are poorly understood. Here we show that dietary restriction (DR) suppresses tumor growth by enhancing CD8 T cell-mediated...
3.
Reyes-Oliveras A, Ellis A, Sheldon R, Haab B
Commun Biol
. 2024 Nov;
7(1):1576.
PMID: 39592729
Cell membrane glycans contribute to immune recognition, signaling, and cellular adhesion and migration, and altered membrane glycosylation is a feature of cancer cells that contributes to cancer progression. The uptake...
4.
Kaluba F, Rogers T, Jeong Y, Waldhart A, Sokol K, Lee C, et al.
bioRxiv
. 2024 Nov;
PMID: 39554134
Cancer cells are exposed to diverse metabolites in the tumor microenvironment that are used to support the synthesis of nucleotides, amino acids, and lipids needed for rapid cell proliferation. Recent...
5.
Rauckhorst A, Sheldon R, Pape D, Ahmed A, Falls-Hubert K, Merrill R, et al.
Cell Metab
. 2024 Oct;
37(1):255-273.e6.
PMID: 39471817
Hepatic de novo lipogenesis (DNL) is a fundamental physiologic process that is often pathogenically elevated in metabolic disease. Treatment is limited by incomplete understanding of the metabolic pathways supplying cytosolic...
6.
Longo J, DeCamp L, Oswald B, Teis R, Reyes-Oliveras A, Dahabieh M, et al.
bioRxiv
. 2024 Oct;
PMID: 39464161
Glucose is essential for T cell proliferation and function, yet its specific metabolic roles remain poorly defined. Here, we identify glycosphingolipid (GSL) biosynthesis as a key pathway fueled by glucose...
7.
Sokol K, Lee C, Rogers T, Waldhart A, Ellis A, Madireddy S, et al.
Cell Chem Biol
. 2024 Oct;
PMID: 39442523
Ferroptosis is a form of cell death caused by lipid peroxidation that is emerging as a target for cancer therapy, highlighting the need to identify factors that govern ferroptosis susceptibility....
8.
Patterson A, Needle G, Sugiura A, Jennings E, Chi C, Steiner K, et al.
Sci Immunol
. 2024 Aug;
9(98):eadh0368.
PMID: 39151020
Inborn errors of metabolism (IEMs) and immunity (IEIs) are Mendelian diseases in which complex phenotypes and patient rarity have limited clinical understanding. Whereas few genes have been annotated as contributing...
9.
Kaymak I, Watson M, Oswald B, Ma S, Johnson B, DeCamp L, et al.
J Exp Med
. 2024 Aug;
221(9).
PMID: 39150482
Coordination of cellular metabolism is essential for optimal T cell responses. Here, we identify cytosolic acetyl-CoA production as an essential metabolic node for CD8 T cell function in vivo. We...
10.
House R, Soper-Hopper M, Vincent M, Ellis A, Capan C, Madaj Z, et al.
Nat Commun
. 2024 Jul;
15(1):5796.
PMID: 38987243
Metabolite extraction is the critical first-step in metabolomics experiments, where it is generally regarded to inactivate and remove proteins. Here, arising from efforts to improve extraction conditions for polar metabolomics,...