Abigail E Ellis
Overview
Explore the profile of Abigail E Ellis including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
125
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0
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Recent Articles
1.
Ma S, Dahabieh M, Mann T, Zhao S, McDonald B, Song W, et al.
Science
. 2024 Dec;
387(6734):eadj3020.
PMID: 39666821
Exhausted T cells (TEX) in cancer and chronic viral infections undergo metabolic and epigenetic remodeling, impairing their protective capabilities. However, the impact of nutrient metabolism on epigenetic modifications that control...
2.
Oswald B, DeCamp L, Longo J, Dahabieh M, Bunda N, Ma S, et al.
bioRxiv
. 2024 Nov;
PMID: 39605550
Reducing calorie intake without malnutrition limits tumor progression but the underlying mechanisms are poorly understood. Here we show that dietary restriction (DR) suppresses tumor growth by enhancing CD8 T cell-mediated...
3.
Reyes-Oliveras A, Ellis A, Sheldon R, Haab B
Commun Biol
. 2024 Nov;
7(1):1576.
PMID: 39592729
Cell membrane glycans contribute to immune recognition, signaling, and cellular adhesion and migration, and altered membrane glycosylation is a feature of cancer cells that contributes to cancer progression. The uptake...
4.
Longo J, DeCamp L, Oswald B, Teis R, Reyes-Oliveras A, Dahabieh M, et al.
bioRxiv
. 2024 Oct;
PMID: 39464161
Glucose is essential for T cell proliferation and function, yet its specific metabolic roles remain poorly defined. Here, we identify glycosphingolipid (GSL) biosynthesis as a key pathway fueled by glucose...
5.
Sokol K, Lee C, Rogers T, Waldhart A, Ellis A, Madireddy S, et al.
Cell Chem Biol
. 2024 Oct;
PMID: 39442523
Ferroptosis is a form of cell death caused by lipid peroxidation that is emerging as a target for cancer therapy, highlighting the need to identify factors that govern ferroptosis susceptibility....
6.
House R, Soper-Hopper M, Vincent M, Ellis A, Capan C, Madaj Z, et al.
Nat Commun
. 2024 Jul;
15(1):5796.
PMID: 38987243
Metabolite extraction is the critical first-step in metabolomics experiments, where it is generally regarded to inactivate and remove proteins. Here, arising from efforts to improve extraction conditions for polar metabolomics,...
7.
Dahabieh M, DeCamp L, Oswald B, Kitchen-Goosen S, Fu Z, Vos M, et al.
bioRxiv
. 2024 Jul;
PMID: 38979360
The progressive decline of CD8 T cell effector function-also known as terminal exhaustion-is a major contributor to immune evasion in cancer. Yet, the molecular mechanisms that drive CD8 T cell...
8.
Sokol K, Lee C, Rogers T, Waldhart A, Ellis A, Madireddy S, et al.
bioRxiv
. 2024 May;
PMID: 38766165
Ferroptosis is a form of cell death caused by lipid peroxidation that is emerging as a target for cancer therapy, highlighting the need to identify factors that govern ferroptosis susceptibility....
9.
Schofield J, Longo J, Sheldon R, Albano E, Ellis A, Hawk M, et al.
Cell Rep
. 2024 Mar;
43(4):113984.
PMID: 38520689
Targeting programmed cell death protein 1 (PD-1) is an important component of many immune checkpoint blockade (ICB) therapeutic approaches. However, ICB is not an efficacious strategy in a variety of...
10.
House R, Tovar E, Redlon L, Essenburg C, Dischinger P, Ellis A, et al.
Mol Metab
. 2024 Jan;
80:101876.
PMID: 38216123
Objective: NF1 is a tumor suppressor gene and its protein product, neurofibromin, is a negative regulator of the RAS pathway. NF1 is one of the top driver mutations in sporadic...