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Eric B Taylor

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Articles 112
Citations 3085
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Recent Articles
1.
Mukherjee U, Basu B, Beyer S, Ghodsi S, Robillard N, Vanrobaeys Y, et al.
bioRxiv . 2025 Mar; PMID: 40027819
Histone post-translational modifications (PTMs), particularly lysine acetylation (Kac), are critical epigenetic regulators of gene transcription underlying long-term memory consolidation. Beyond Kac, several other non-acetyl acylations have been identified, but their...
2.
Bartlett J, Huntemann E, Krishnamurthy S, Hartwig S, Pewa A, Thurman A, et al.
J Cyst Fibros . 2025 Feb; PMID: 39956716
Background: In individuals with cystic fibrosis (CF), respiratory viral infections frequently result in hospitalization and have been linked to secondary bacterial infection and colonization, highlighting viral infections as possible contributors...
3.
Som R, Fink B, Rauckhorst A, Taylor E, Sivitz W
J Bioenerg Biomembr . 2025 Feb; PMID: 39954225
Glutamine is well recognized as critical to the growth of most cell types. Within mitochondria glutamine is converted to glutamate by glutaminase. Oxaloacetate and glutamate then react to form alpha-ketoglutarate...
4.
Kim B, Rauckhorst A, Chimenti M, Rehman T, Keen H, Karp P, et al.
Sci Adv . 2025 Jan; 11(4):eadr2282. PMID: 39854459
Oxygen controls most metazoan metabolism, yet in mammals, tissue O levels vary widely. While extensive research has explored cellular responses to hypoxia, understanding how cells respond to physiologically high O...
5.
Guppy B, Mitchell C, Taylor E
Bull Math Biol . 2024 Nov; 87(1):7. PMID: 39601930
Metabolic fluxes are the rates of life-sustaining chemical reactions within a cell and metabolites are the components. Determining the changes in these fluxes is crucial to understanding diseases with metabolic...
6.
Rauckhorst A, Sheldon R, Pape D, Ahmed A, Falls-Hubert K, Merrill R, et al.
Cell Metab . 2024 Oct; 37(1):255-273.e6. PMID: 39471817
Hepatic de novo lipogenesis (DNL) is a fundamental physiologic process that is often pathogenically elevated in metabolic disease. Treatment is limited by incomplete understanding of the metabolic pathways supplying cytosolic...
7.
Pape D, Falls-Hubert K, Merrill R, Ahmed A, Qian Q, McGivney G, et al.
bioRxiv . 2024 Sep; PMID: 39314408
Hepatic gluconeogenesis (GNG) is essential for maintaining euglycemia during prolonged fasting. However, GNG becomes pathologically elevated and drives chronic hyperglycemia in type 2 diabetes (T2D). Lactate/pyruvate is a major GNG...
8.
Guppy B, Mitchell C, Taylor E
ArXiv . 2024 Jul; PMID: 39040651
Metabolic fluxes are the rates of life-sustaining chemical reactions within a cell and metabolites are the components. Determining the changes in these fluxes is crucial to understanding diseases with metabolic...
9.
Liu A, Geraldes A, Taylor E
Mol Ecol . 2024 Jul; 33(15):e17459. PMID: 38994921
Hybridization between divergent lineages can result in losses of distinct evolutionary taxa. Alternatively, hybridization can lead to increased genetic variability that may fuel local adaptation and the generation of novel...
10.
Schultz J, Gander P, Workman C, Ponto L, Cross S, Nance C, et al.
medRxiv . 2024 Jun; PMID: 38826433
Background: Parkinson's disease (PD) is a prevalent neurodegenerative disorder where progressive neuron loss is driven by impaired brain bioenergetics, particularly mitochondrial dysfunction and disrupted cellular respiration. Terazosin (TZ), an α-1...