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Ruth Tal-Singer

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Articles 209
Citations 9811
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Recent Articles
1.
Vila M, Agusti A, Vestbo J, Celli B, Cosio B, Silverman E, et al.
ERJ Open Res . 2025 Feb; 11(1). PMID: 40008176
Background: The ECLIPSE study was a large, international, prospective, controlled, observational study that included COPD patients (Global Initiative for Chronic Obstructive Lung Disease (GOLD) grades 2-4), as well as smoking...
2.
Mercuri F, Anderson G, Miller B, Demaison C, Tal-Singer R
Antiviral Res . 2024 Dec; 234():106063. PMID: 39733845
Viral respiratory infection is associated with significant morbidity and mortality. The diversity of viruses implicated, coupled with their propensity for mutation, ignited an interest in host-directed antiviral therapies effective across...
3.
Mercuri F, White S, McQuilten H, Lemech C, Mynhardt S, Hari R, et al.
ERJ Open Res . 2024 Dec; 10(6). PMID: 39655168
Background: Local priming of the innate immune system with a Toll-like receptor (TLR)2/6 agonist may reduce morbidity and mortality associated with viral respiratory tract infections, particularly for the elderly and...
4.
Roman-Rodriguez M, McMullan I, Warner M, Compton C, Tal-Singer R, Orlow J, et al.
Patient Prefer Adherence . 2024 Nov; 18:2295-2306. PMID: 39559482
Purpose: Asthma and chronic obstructive pulmonary disease (COPD) are associated with substantial morbidity and mortality. This analysis assessed patient, caregiver, and healthcare provider (HCP) opinions regarding asthma and COPD diagnosis...
5.
Moll M, Hecker J, Platig J, Zhang J, Ghosh A, Pratte K, et al.
EBioMedicine . 2024 Nov; 110:105429. PMID: 39509750
Background: Genetic variants and gene expression predict risk of chronic obstructive pulmonary disease (COPD), but their effect on COPD heterogeneity is unclear. We aimed to define high-risk COPD subtypes using...
6.
Harvey-Dunstan T, Baldwin M, Tal-Singer R, Allinder M, Polkey M, Hamilton A, et al.
Chest . 2024 Aug; 167(1):98-111. PMID: 39173827
Background: COPD is characterized by reduced exercise tolerance, and improving physical performance is an important therapeutic goal. A variety of exercise tests are commonly used to assess exercise tolerance, including...
7.
Moll M, Hecker J, Platig J, Zhang J, Ghosh A, Pratte K, et al.
medRxiv . 2024 Jun; PMID: 38826461
Rationale: Genetic variants and gene expression predict risk of chronic obstructive pulmonary disease (COPD), but their effect on COPD heterogeneity is unclear. Objectives: Define high-risk COPD subtypes using both genetics...
8.
Aksamit T, Locantore N, Addrizzo-Harris D, Ali J, Barker A, Basavaraj A, et al.
Am J Respir Crit Care Med . 2024 Apr; 210(1):108-118. PMID: 38668710
Nontuberculous mycobacteria (NTM) are prevalent among patients with bronchiectasis. However, the long-term natural history of patients with NTM and bronchiectasis is not well described. To assess the impact of NTM...
9.
Shrine N, Guyatt A, Erzurumluoglu A, Jackson V, Hobbs B, Melbourne C, et al.
Nat Genet . 2024 Apr; 56(5):1032-1033. PMID: 38641645
No abstract available.
10.
Shek N, Choy A, Lang C, Miller B, Tal-Singer R, Bolton C, et al.
NPJ Aging . 2024 Feb; 10(1):15. PMID: 38413600
Aging is a major driving force for many diseases but the relationship between chronological age, the aging process and age-related diseases is not fully understood. Fragmentation and loss of ultra-long-lived...