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Russ Ellis

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Articles 21
Citations 605
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Recent Articles
1.
Petre M, Petrik J, Ellis R, Inman M, Holloway A, Labiris N
Int J Toxicol . 2011 Mar; 30(2):244-52. PMID: 21378373
Many women are unable to quit smoking during pregnancy and therefore are prescribed drugs, including nicotine (nicotine replacement therapy [NRT]), to aid with smoking cessation. However, the consequences to the...
2.
Hirota J, Ask K, Farkas L, Smith J, Ellis R, Rodriguez-Lecompte J, et al.
Am J Respir Cell Mol Biol . 2011 Jan; 45(3):566-72. PMID: 21216974
Airway smooth muscle (ASM) hyperplasia in asthma likely contributes considerably to functional changes. Investigating the mechanisms behind proliferation of these cells may lead to therapeutic benefit. Platelet-derived growth factor (PDGF)-BB...
3.
Swedin L, Ellis R, Kemi C, Ryrfeldt A, Inman M, Dahlen S, et al.
Int Arch Allergy Immunol . 2010 May; 153(3):249-58. PMID: 20484923
Background: The aim was to optimize antigen challenge for induction of airway hyperresponsiveness (AHR) and inflammation in BALB/c mice sensitized to ovalbumin (OVA). Comparisons were made between mice challenged with...
4.
Khan M, Ellis R, Inman M, Bates J, Sanderson M, Janssen L
Am J Physiol Lung Cell Mol Physiol . 2010 May; 299(1):L98-L108. PMID: 20435686
Understanding how tissue remodeling affects airway responsiveness is of key importance, but experimental data bearing on this issue remain scant. We used lung explants to investigate the effects of enzymatic...
5.
Swedin L, Ellis R, Neimert-Andersson T, Ryrfeldt A, Nilsson G, Inman M, et al.
Prostaglandins Other Lipid Mediat . 2010 Mar; 92(1-4):44-53. PMID: 20214998
As adjuvant during sensitization may cause unspecific immune reactions, the aim of the present study was to define the role of cyclooxygenase (COX) activity on airway inflammation and airway hyperresponsiveness...
6.
DiGiovanni F, Ellis R, Wattie J, Hirota J, Southam D, Inman M
Dis Model Mech . 2009 Apr; 2(5-6):275-82. PMID: 19380307
Experimental mouse models of asthma have broadened our understanding of the mechanisms behind allergen-induced asthma. Typically, mouse models of allergic asthma explore responses to a single allergen; however, patients with...
7.
Southam D, Ellis R, Wattie J, Glass W, Inman M
Am J Respir Crit Care Med . 2008 Oct; 178(11):1115-22. PMID: 18849499
Rationale: Although corticosteroids are highly effective at preventing allergen-induced increases in goblet cell numbers, we observed in unpublished experiments a rebound increase in goblet cell numbers in mice after the...
8.
Southam D, Ellis R, Wattie J, Inman M
J Allergy Clin Immunol . 2007 Feb; 119(4):848-54. PMID: 17321577
Background: Pathologic changes, including inflammation and remodeling, occur in the asthmatic airway. However, their relative contribution to the components of airway hyperresponsiveness (AHR) remains unclear. Objective: Attempting to delineate AHR...
9.
Hirota J, Ellis R, Inman M
Respir Res . 2006 Sep; 7:120. PMID: 16989666
Background: Airway remodeling present in the large airways in asthma or asthma models has been associated with airway dysfunction in humans and mice. It is not clear if airways distal...
10.
Southam D, Widmer N, Ellis R, Hirota J, Inman M, Sehmi R
J Allergy Clin Immunol . 2005 Jan; 115(1):95-102. PMID: 15637553
Background: There is increasing evidence that hemopoietic progenitor cells may traffic from bone marrow to sites of allergen exposure in asthma and undergo in situ differentiation, contributing to ongoing airway...