Klaus I Matthaei
Overview
Explore the profile of Klaus I Matthaei including associated specialties, affiliations and a list of published articles.
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59
Citations
1909
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Recent Articles
1.
Morton S, Chaston D, Howitt L, Heisler J, Nicholson B, Fairweather S, et al.
Hypertension
. 2014 Dec;
65(3):662-9.
PMID: 25547341
During activity, coordinated vasodilation of microcirculatory networks with upstream supply vessels increases blood flow to skeletal and cardiac muscles and reduces peripheral resistance. Endothelial dysfunction in humans attenuates activity-dependent vasodilation,...
2.
Su Y, Townsend D, Herrero L, Zaid A, Rolph M, Gahan M, et al.
J Virol
. 2014 Nov;
89(3):1564-78.
PMID: 25410867
Unlabelled: Human respiratory syncytial virus (RSV) is a major cause of morbidity and severe lower respiratory tract disease in the elderly and very young, with some infants developing bronchiolitis, recurrent...
3.
Chaston D, Haddock R, Howitt L, Morton S, Brown R, Matthaei K, et al.
Pflugers Arch
. 2014 Nov;
467(9):1997-2009.
PMID: 25369777
Mutant forms of connexin40 (Cx40) exist in the human population and predispose carriers to atrial fibrillation. Since endothelial expression of Cx40 is important for electrical and chemical communication within the...
4.
Howitt L, Matthaei K, Drummond G, Hill C
Pflugers Arch
. 2014 Jun;
467(4):727-35.
PMID: 24923576
Cardiovascular disease is characterised by reduced nitric oxide bioavailability resulting from oxidative stress. Our previous studies have shown that nitric oxide deficit per se increases the contribution of T-type calcium...
5.
Bhat P, Leggatt G, Matthaei K, Frazer I
PLoS One
. 2014 May;
9(5):e95248.
PMID: 24801876
Cytotoxic lymphocytes (CTL) have been reported to show a range of motility patterns from rapid long-range tracking to complete arrest, but how and whether these kinematics affect their ability to...
6.
Morton S, Chaston D, Baillie B, Hill C, Matthaei K
PLoS One
. 2014 Apr;
9(4):e95980.
PMID: 24755679
Genetically modified mice have played an important part in elucidating gene function in vivo. However, conclusions from transgenic studies may be compromised by complications arising from the site of transgene...
7.
Poon I, Goodall K, Phipps S, Chow J, Pagler E, Andrews D, et al.
Eur J Immunol
. 2014 Feb;
44(4):1016-30.
PMID: 24532362
Heparanase is a β-d-endoglucuronidase that cleaves heparan sulphate, a key component of the ECM and basement membrane. The remodelling of the ECM by heparanase has been proposed to regulate both...
8.
Frese M, Lee E, Larena M, Lim P, Rao S, Matthaei K, et al.
J Virol
. 2013 Dec;
88(4):2056-70.
PMID: 24307589
Infectious clone technologies allow the rational design of live attenuated viral vaccines with the possibility of vaccine-driven coexpression of immunomodulatory molecules for additional vaccine safety and efficacy. The latter could...
9.
Paz-Filho G, Mastronardi C, Parker B, Khan A, Inserra A, Matthaei K, et al.
J Mol Endocrinol
. 2013 May;
51(1):167-79.
PMID: 23718963
Unlabelled: Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis are components of the metabolic syndrome. Serum leptin levels are elevated in obesity, but the role of leptin in the pathophysiology...
10.
Chaston D, Baillie B, Grayson T, Courjaret R, Heisler J, Lau K, et al.
Arterioscler Thromb Vasc Biol
. 2013 Mar;
33(5):962-70.
PMID: 23471232
Objective: To determine whether impairment of endothelial connexin40 (Cx40), an effect that can occur in hypertension and aging, contributes to the arterial dysfunction and stiffening in these conditions. Approach And...