Roshan K Sriram
Overview
Explore the profile of Roshan K Sriram including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
985
Followers
0
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Recent Articles
1.
Li J, Duran M, Dhanota N, Chatila W, Bettigole S, Kwon J, et al.
Cancer Discov
. 2020 Dec;
11(5):1212-1227.
PMID: 33372007
Cytosolic DNA is characteristic of chromosomally unstable metastatic cancer cells, resulting in constitutive activation of the cGAS-STING innate immune pathway. How tumors co-opt inflammatory signaling while evading immune surveillance remains...
2.
Ngo B, Kim E, Osorio-Vasquez V, Doll S, Bustraan S, Liang R, et al.
Cancer Discov
. 2020 Jun;
10(9):1352-1373.
PMID: 32571778
A hallmark of metastasis is the adaptation of tumor cells to new environments. Metabolic constraints imposed by the serine and glycine-limited brain environment restrict metastatic tumor growth. How brain metastases...
3.
Bakhoum S, Ngo B, Laughney A, Cavallo J, Murphy C, Ly P, et al.
Nature
. 2018 Jan;
553(7689):467-472.
PMID: 29342134
Chromosomal instability is a hallmark of cancer that results from ongoing errors in chromosome segregation during mitosis. Although chromosomal instability is a major driver of tumour evolution, its role in...
4.
Al-Zahrani K, Sekhon P, Tessier D, Yockell-Lelievre J, Pryce B, Baron K, et al.
Dev Dyn
. 2014 May;
243(5):640-51.
PMID: 24868594
Background: Over the past decade, the Ste20-like kinase SLK, has been implicated in several signaling processes. SLK repression has been shown to impair cell cycle kinetics and inhibit FAK-mediated cell...