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Rong-Guang Shao

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Articles 80
Citations 981
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Recent Articles
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Li G, Duan Y, Wang Y, Bian L, Xiong M, Song W, et al.
Environ Pollut . 2022 Apr; 305:119308. PMID: 35443204
Numerous epidemiological studies have shown a close relationship between outdoor air pollution and increased risks for cancer, infection, and cardiopulmonary diseases. However, very few studies have investigated the potential health...
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Qiu Y, Zhang T, Wang X, Wang M, Zhao W, Zhou H, et al.
J Drug Target . 2021 Feb; 29(6):576-591. PMID: 33554661
Mitophagy is a selective form of macroautophagy in which dysfunctional and damaged mitochondria can be efficiently degraded, removed and recycled through autophagy. Selective removal of damaged or fragmented mitochondria is...
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Zhang C, Liu H, Zhao W, Zhao W, Zhou H, Shao R
Acta Pharmacol Sin . 2021 Feb; 42(11):1900-1912. PMID: 33536604
Ras-GTPase activating SH3 domain-binding protein 1 (G3BP1) is a multifunctional binding protein involved in the development of a variety of human cancers. However, the role of G3BP1 in breast cancer...
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Song W, Zheng S, Yao H, Zhou X, Li R, Zhang C, et al.
BMC Ophthalmol . 2020 Mar; 20(1):92. PMID: 32143590
Background: Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological...
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Zhao W, Xing Y, Ye C, Qiu Y, Li Y, Liu X, et al.
Acta Pharmacol Sin . 2020 Jan; 41(5):686-697. PMID: 31932645
Sophoridine is a quinolizidine natural product and the exploration of its derivatives has been carried out, and the potent anticancer compound IMB-HDC was acquired. Although previous studies have revealed that...
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Zhang N, Zhao S, Zhang Y, Wang Y, Shao R, Wang J, et al.
Acta Pharmacol Sin . 2020 Jan; 41(5):661-669. PMID: 31932644
Chronic tissue injury with fibrosis results in the disruption of tissue architecture, organ dysfunction, and eventual organ failure. Therefore, the development of effective antifibrotic drugs is urgently required. IMB-S7 is...
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Ge M, Liu H, Zhang N, Niu W, Lu Z, Bao Y, et al.
Br J Pharmacol . 2019 Oct; 177(2):372-387. PMID: 31621893
Background And Purpose: This study investigates the antifibrotic activities and potential mechanisms of costunolide (COS), a natural sesquiterpene compound. Experimental Approach: Rats subjected to bile duct ligation and mice challenged...
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Wang M, Qiu Y, Cai M, Zhang C, Wang X, Liu H, et al.
J Drug Target . 2019 Jun; 28(1):1-10. PMID: 31244351
In recent years, the rate of colorectal cancer has sharply increased, especially in China, where it ranks second for the number of cancer fatalities. Currently, the treatment of colorectal cancer...
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Cai M, Wang M, Zhang C, Wang J, Liu H, He H, et al.
J Drug Target . 2019 May; 28(1):23-32. PMID: 31094236
Src family kinases (SFKs) are non-receptor tyrosine kinases and are involved in various cellular functions (proliferation, differentiation, migration, survival and invasion) by regulating downstream pathways. Considerable evidence suggests that co-...