Rong-Guang Shao
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Explore the profile of Rong-Guang Shao including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Ge M, Shao R, He H
Biochem Pharmacol
. 2019 Apr;
164:152-164.
PMID: 30978324
The conversion of cholesterol to bile acids (BAs) contributes to the elimination of total cholesterol from the body. In addition, manipulating BA homeostasis by modulating cholesterol 7α-hydroxylase (CYP7A1) may affect...
12.
Ge M, Niu W, Ren J, Cai S, Yu D, Liu H, et al.
Acta Pharmacol Sin
. 2018 Dec;
40(7):895-907.
PMID: 30573812
The manipulation of bile acid (BA) homeostasis by blocking the ileal apical Na-dependent bile salt transporter (ASBT/SLC10A2) may have therapeutic effects in nonalcoholic fatty liver disease. We developed a novel...
13.
Li L, Hu L, Zhao C, Zhang S, Wang R, Li Y, et al.
Bioconjug Chem
. 2018 Aug;
29(9):3104-3112.
PMID: 30105903
Depending on increasing extracellular protein utilization and altering metabolic programs, cancer cells could proliferate and survive without restricion by ingesting human serum albumin (HSA) to serve as nutritional amino acids....
14.
Ge M, Wang J, Shao R, He H
Yao Xue Xue Bao
. 2018 Jul;
52(2):189-97.
PMID: 29979499
Bile acids play critical roles in the regulation of metabolism and absorption of lipids. The ileal
apical sodium-dependent bile acid transporter (ASBT) located at the enterocyte brush border is responsible...
15.
Chen Y, Sun W, He R, Zhang F, Wang H, Li P, et al.
Oncol Lett
. 2018 Jan;
14(6):7889-7895.
PMID: 29344233
Cluster of differentiation (CD)133 is considered a molecular marker of cancer stem cells in hepatocellular carcinoma. In the present study, the effect of lidamycin (LDM) on CD133 expression in hepatocellular...
16.
Liu H, Zhao W, Wang J, Xin B, Shao R
Acta Pharmacol Sin
. 2017 Dec;
39(8):1347-1358.
PMID: 29283175
c-Myc, a key activator of cell proliferation and angiogenesis, promotes the development and progression of breast cancer. Ezrin-radixin-moesin-binding phosphoprotein-50 (EBP50) is a multifunctional scaffold protein that suppresses the proliferation of...
17.
Zhao S, Li N, Zhao W, Liu H, Ge M, Zhang Y, et al.
Acta Pharmacol Sin
. 2017 Jul;
39(2):213-221.
PMID: 28748913
Cholestatic liver diseases are important causes of liver cirrhosis and liver transplantation, but few drugs are available for treatment. D-chiro-inositol (DCI), an isomer of inositol found in many Leguminosae plants...
18.
Liu H, Ma Y, He H, Zhao W, Shao R
Autophagy
. 2017 May;
13(5):900-913.
PMID: 28521610
SPHK1 (sphingosine kinase 1), a regulator of sphingolipid metabolites, plays a causal role in the development of hepatocellular carcinoma (HCC) through augmenting HCC invasion and metastasis. However, the mechanism by...
19.
Ge M, Liu H, Zhang Y, Li N, Zhao S, Zhao W, et al.
Br J Pharmacol
. 2017 Mar;
174(10):1147-1160.
PMID: 28257144
Background And Purpose: Dihydrotanshinone I (DHI), a lipophilic component of traditional Chinese medicine Salvia miltiorrhiza Bunge, has various therapeutic effects. We investigated the anti-fibrotic effect of DHI and its underlying...
20.
Ge M, He H, Shao R, Liu H
J Asian Nat Prod Res
. 2017 Jan;
19(2):109-113.
PMID: 28133978
Hepatic fibrosis is a wound-healing response to chronic liver injury caused by various pathogenesis, such as hepatitis virus infection, drugs toxicity and autoimmune imbalances. Autophagy, a cellular process degrading damaged...