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Sheng-Hua Zhang

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Articles 45
Citations 271
Followers 0
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Recent Articles
1.
Li L, Hu L, Zhao C, Zhang S, Wang R, Li Y, et al.
Bioconjug Chem . 2018 Aug; 29(9):3104-3112. PMID: 30105903
Depending on increasing extracellular protein utilization and altering metabolic programs, cancer cells could proliferate and survive without restricion by ingesting human serum albumin (HSA) to serve as nutritional amino acids....
2.
Liu W, Liu X, Xu J, Li L, Li Y, Zhang S, et al.
Acta Pharmacol Sin . 2018 Jul; 39(11):1777-1786. PMID: 30013033
Defensins play an essential role in innate immunity. In this study, a novel recombinant β-defensin that targets the epidermal growth factor receptor (EGFR) was designed and prepared. The EGFR-targeting β-defensin...
3.
Zhang S, Zhang S, Zhang X, Wang G
Huan Jing Ke Xue . 2018 Jul; 38(6):2419-2428. PMID: 29965361
As an effective technology for wastewater treatment, bio-filter has been widely used. Nevertheless, there is still a lack of systematic report on purification efficiency and influencing factors of combined bio-filters....
4.
Xu J, Du Y, Liu X, Zhu B, Zhang S, Li L, et al.
Pharmacol Res . 2017 Apr; 126:66-76. PMID: 28392461
Overexpression of EGFR and MMP-2 plays an essential role in the initiation and progression of non-small-cell lung carcinoma (NSCLC). In this study, a novel format of EGFR/MMP-2 bi-targeted fusion protein...
5.
Du Y, Shang B, Sheng W, Zhang S, Li Y, Miao Q, et al.
Oncotarget . 2016 Aug; 7(36):58418-58434. PMID: 27517152
K-Ras mutant pancreatic cancer cells display intensive macropinocytosis, indicating that this process may be exploited in the design of anticancer targeted therapies. In this study, we constructed a macropinocytosis-oriented recombinantly...
6.
Xu J, Liu X, Li L, Zhang S, Li Y, Gao R, et al.
Oncotarget . 2015 Aug; 6(28):26322-34. PMID: 26314845
Recent studies have shown that MMP-14 is highly expressed in a panel of human solid tumors and poses as a potential molecular target for anticancer drugs. Currently, major strategies for...
7.
Yu D, Zhang C, Zhao S, Zhang S, Zhang H, Cai S, et al.
Acta Pharmacol Sin . 2015 Apr; 36(4):473-82. PMID: 25832428
Aim: (-)-Epigallocatechin-3-gallate (EGCG) is one of the most abundant polyphenols in green tea with strong antioxidant activity and various therapeutic effects. In this study, we investigated the anti-fibrotic effects of...
8.
Liu W, Liu X, Li L, Li Y, Zhang S, Zhen Y
Cancer Immunol Immunother . 2014 Aug; 63(12):1261-72. PMID: 25164878
Tuftsin (TF) is an immunomodulator tetrapeptide (Thr-Lys-Pro-Arg) that binds to the receptor neuropilin-1 (Nrp1) on the surface of cells. Many reports have described anti-tumor activity of tuftsin to relate with...
9.
Li X, Ouyang Z, Zhang S, Liu H, Shang Y, Li Y, et al.
J Neurooncol . 2014 May; 119(1):91-100. PMID: 24842385
The present work evaluated the synergistic efficacy of an enediyne antibiotic lidamycin (LDM) plus temozolomide (TMZ) against glioma in vitro and in vivo. LDM plus TMZ inhibited the proliferations of...
10.
Sun Y, Zhang S, Shao R, He H
Yao Xue Xue Bao . 2014 Apr; 49(2):198-203. PMID: 24761609
This study aimed to investigate the synergistic effect of lidamycin (LDM) and rituximab on human B cell lymphoma Ramos cells. Cell proliferation was measured using MTS assay, cell apoptosis was...