Roland M Schaefer
Overview
Explore the profile of Roland M Schaefer including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
36
Citations
1598
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Engelen M, Brand E, Baumeister T, Marquardt T, Duning T, Osada N, et al.
BMJ Open
. 2012 Nov;
2(6).
PMID: 23175739
Objective: Fabry disease (FD) is an X-linked inborn error of glycosphingolipid catabolism caused by deficient lysosomal α-galactosidase A activity. Progressive accumulation of globotriaosylceramide and related glycosphingolipids in vascular endothelial lysosomes...
2.
Merline R, Moreth K, Beckmann J, Nastase M, Zeng-Brouwers J, Tralhao J, et al.
Sci Signal
. 2011 Nov;
4(199):ra75.
PMID: 22087031
The mechanisms linking immune responses and inflammation with tumor development are not well understood. Here, we show that the soluble form of the extracellular matrix proteoglycan decorin controls inflammation and...
3.
Palmes D, Kebschull L, Schaefer R, Pelster F, Konner K
Nephrol Dial Transplant
. 2011 Feb;
26(10):3309-14.
PMID: 21325347
Background: Access-related problems are one of the major causes of morbidity in elderly patients with chronic kidney disease. The aim of this study was to assess potential risks and benefits...
4.
Moreth K, Brodbeck R, Babelova A, Gretz N, Spieker T, Zeng-Brouwers J, et al.
J Clin Invest
. 2010 Nov;
120(12):4251-72.
PMID: 21084753
CXCL13 is a key B cell chemoattractant and marker of disease activity in patients with SLE; however, the mechanism of its induction has not been identified yet. Here, we have...
5.
Mignani R, Feriozzi S, Schaefer R, Breunig F, Oliveira J, Ruggenenti P, et al.
Clin J Am Soc Nephrol
. 2010 Jan;
5(2):379-85.
PMID: 20056752
ESRD is a major cause of morbidity and premature mortality in Fabry disease, particularly in classically affected males. The decline of renal function in Fabry nephropathy is adversely affected by...
6.
Schaefer R, Tylki-Szymanska A, J Hilz M
Drugs
. 2009 Oct;
69(16):2179-205.
PMID: 19852524
Fabry disease is a progressive and life-threatening glycolipid storage disorder affecting both males and females. The primary driver of the disease is the accumulation of glycolipids (globotriaosylceramide [GL-3]) in a...
7.
Merline R, Schaefer R, Schaefer L
J Cell Commun Signal
. 2009 Oct;
3(3-4):323-35.
PMID: 19809894
The small leucine-rich proteoglycans (SLRPs) are biologically active components of the extracellular matrix (ECM), consisting of a protein core with leucine rich-repeat (LRR) motifs covalently linked to glycosaminoglycan (GAG) side...
8.
Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young M, et al.
J Biol Chem
. 2009 Jul;
284(36):24035-48.
PMID: 19605353
The role of endogenous inducers of inflammation is poorly understood. To produce the proinflammatory master cytokine interleukin (IL)-1beta, macrophages need double stimulation with ligands to both Toll-like receptors (TLRs) for...
9.
Schaefer L, Schaefer R
Cell Tissue Res
. 2009 Jun;
339(1):237-46.
PMID: 19513755
Our knowledge of proteoglycan biology has significantly expanded over the past decade with the discovery of a host of new members of this multifunctional family leading to their present classification...
10.
Holscher B, Heitmeyer C, Fobker M, Breithardt G, Schaefer R, Reinecke H
Can J Cardiol
. 2008 Nov;
24(11):845-50.
PMID: 18987758
Background: Among the numerous studies concerning contrast media-induced nephropathy (CIN), there was no prospective trial that provided data on the long-term outcomes. Objectives: To prospectively assess predictors of CIN and...