Roland Gamsjaeger
Overview
Explore the profile of Roland Gamsjaeger including associated specialties, affiliations and a list of published articles.
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42
Citations
811
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Recent Articles
1.
Zhong Y, Wilkinson-White L, Zhang E, Mohanty B, Zhang B, McRae M, et al.
PLoS One
. 2024 Sep;
19(9):e0310565.
PMID: 39283902
RNA-binding proteins (RBPs) are a major class of proteins that interact with RNAs to change their fate or function. RBPs and the ribonucleoprotein complexes they constitute are involved in many...
2.
Baker D, Wang B, Wilkinson-White L, El-Kamand S, Allport T, Ataide S, et al.
Proteins
. 2024 Jul;
92(11):1308-1317.
PMID: 38958516
The ongoing global pandemic of the coronavirus 2019 (COVID-19) disease is caused by the virus SARS-CoV-2, with very few highly effective antiviral treatments currently available. The machinery responsible for the...
3.
Croft L, Fisher M, Barbhuiya T, El-Kamand S, Beard S, Rajapakse A, et al.
Nucleic Acid Ther
. 2024 Apr;
34(3):143-155.
PMID: 38648015
Single-stranded oligonucleotides (SSOs) are a rapidly expanding class of therapeutics that comprises antisense oligonucleotides, microRNAs, and aptamers, with ten clinically approved molecules. Chemical modifications such as the phosphorothioate backbone and...
4.
Mani G, El-Kamand S, Wang B, Baker D, Ataide S, Artsimovitch I, et al.
Proteins
. 2023 Nov;
92(3):418-426.
PMID: 37929701
Middle East respiratory syndrome coronavirus (MERS CoV) and severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) are RNA viruses from the Betacoronavirus family that cause serious respiratory illness in humans....
5.
El-Kamand S, Adams M, Matthews J, Du Plessis M, Crossett B, Connolly A, et al.
Protein Sci
. 2023 Sep;
32(10):e4782.
PMID: 37705456
The repair of double-strand DNA breaks (DSBs) by homologous recombination is crucial in the maintenance of genome integrity. While the key role of the Mre11-Rad50-Nbs1 (MRN) complex in repair is...
6.
Jayawardena B, Peacey L, Gamsjaeger R, Jones C
Biomolecules
. 2022 Nov;
12(11).
PMID: 36358935
Neurokinin B is a tachykinin peptide involved in a diverse range of neuronal functions. It rapidly forms an amyloid, which is considered physiologically important for efficient packing into dense core...
7.
Boucher D, Kariawasam R, Burgess J, Gimenez A, Ocampo T, Ferguson B, et al.
Sci Rep
. 2021 Oct;
11(1):20256.
PMID: 34642383
Maintenance of genomic stability is critical to prevent diseases such as cancer. As such, eukaryotic cells have multiple pathways to efficiently detect, signal and repair DNA damage. One common form...
8.
El-Kamand S, Du Plessis M, Breen N, Johnson L, Beard S, Kwan A, et al.
Proteins
. 2021 Aug;
90(1):176-185.
PMID: 34369011
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel, highly infectious RNA virus that belongs to the coronavirus family. Replication of the viral genome is a fundamental step in...
9.
El-Kamand S, Du Plessis M, Lawson T, Cubeddu L, Gamsjaeger R
Methods Mol Biol
. 2021 Apr;
2281:229-240.
PMID: 33847962
Single-stranded DNA-binding proteins (SSBs) are essential to all living organisms as protectors and guardians of the genome. Apart from the well-characterized RPA, humans have also evolved two further SSBs, termed...
10.
Lawson T, El-Kamand S, Boucher D, Duong D, Kariawasam R, Bonvin A, et al.
Proteins
. 2019 Aug;
88(2):319-326.
PMID: 31443132
Single-stranded DNA-binding proteins (SSBs) are required for all known DNA metabolic events such as DNA replication, recombination and repair. While a wealth of structural and functional data is available on...