Roderick T Bronson
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Explore the profile of Roderick T Bronson including associated specialties, affiliations and a list of published articles.
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321
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Recent Articles
1.
Freie B, Ibrahim A, Carroll P, Bronson R, Augert A, MacPherson D, et al.
bioRxiv
. 2024 Oct;
PMID: 39386474
The MYC transcription factor requires MAX for DNA binding and widespread activation of gene expression in both normal and neoplastic cells. Surprisingly, inactivating mutations in are associated with a subset...
2.
Shah P, Romar G, Manukyan A, Ko W, Hsieh P, Velasquez G, et al.
J Clin Invest
. 2024 Jul;
134(17).
PMID: 39042477
Delayed-type drug hypersensitivity reactions are major causes of morbidity and mortality. The origin, phenotype, and function of pathogenic T cells across the spectrum of severity require investigation. We leveraged recent...
3.
Asantewaa G, Tuttle E, Ward N, Kang Y, Kim Y, Kavanagh M, et al.
Nat Commun
. 2024 Jul;
15(1):6152.
PMID: 39034312
Cells rely on antioxidants to survive. The most abundant antioxidant is glutathione (GSH). The synthesis of GSH is non-redundantly controlled by the glutamate-cysteine ligase catalytic subunit (GCLC). GSH imbalance is...
4.
Wu J, Deng J, Theocharidis G, Sarrafian T, Griffiths L, Bronson R, et al.
Nature
. 2024 May;
630(8016):360-367.
PMID: 38778109
Implanted biomaterials and devices face compromised functionality and efficacy in the long term owing to foreign body reactions and subsequent formation of fibrous capsules at the implant-tissue interfaces. Here we...
5.
Min J, Zaslavsky A, Fedele G, McLaughlin S, Reczek E, De Raedt T, et al.
Nat Med
. 2024 Feb;
30(6):1790.
PMID: 38383797
No abstract available.
6.
Guo W, Ortega E, Wu D, Li L, Bronson R, Boehm S, et al.
Front Nutr
. 2023 Dec;
10:1286792.
PMID: 38125727
Objective: Epidemiological studies suggest that consumption of fruits and vegetables (FV) is negatively associated with the incidence of certain cancers and mortality. However, a causal relationship has not been demonstrated....
7.
Li Y, Mahadevan N, Duplaquet L, Hong D, Durmaz Y, Jones K, et al.
Cell Rep Med
. 2023 Nov;
4(11):101282.
PMID: 37992688
Despite small cell lung cancers (SCLCs) having a high mutational burden, programmed death-ligand 1 (PD-L1) immunotherapy only modestly increases survival. A subset of SCLCs that lose their ASCL1 neuroendocrine phenotype...
8.
He A, Tian S, Kopper O, Horan D, Chen P, Bronson R, et al.
PLoS Biol
. 2023 Nov;
21(11):e3002353.
PMID: 37943878
Wnt signaling pathways are transmitted via 10 homologous frizzled receptors (FZD1-10) in humans. Reagents broadly inhibiting Wnt signaling pathways reduce growth and metastasis of many tumors, but their therapeutic development...
9.
Sarin K, Kincaid J, Sell B, Shahryari J, Duncton M, Morefield E, et al.
Sci Transl Med
. 2023 Oct;
15(717):eade1844.
PMID: 37820007
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer. Although cSCC contributes to substantial morbidity and mortality in high-risk individuals, deployment of otherwise effective chemoprevention of cSCC...
10.
Westcott P, Muyas F, Hauck H, Smith O, Sacks N, Ely Z, et al.
Nat Genet
. 2023 Sep;
55(10):1686-1695.
PMID: 37709863
DNA mismatch repair deficiency (MMRd) is associated with a high tumor mutational burden (TMB) and sensitivity to immune checkpoint blockade (ICB) therapy. Nevertheless, most MMRd tumors do not durably respond...