Robert V Stahelin
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Explore the profile of Robert V Stahelin including associated specialties, affiliations and a list of published articles.
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3815
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Recent Articles
1.
Arce A, Altman R, Badolian A, Low J, Cuaresma A, Keshet U, et al.
bioRxiv
. 2025 Mar;
PMID: 40027828
HSPA1A, a major heat shock protein, is known to translocate to the plasma membrane (PM) in response to cellular stress and cancer, where it plays protective roles in membrane integrity...
2.
Abeywickrama C, Huang E, Yan W, Vrionides M, Warushavithana P, Johnson K, et al.
Biosensors (Basel)
. 2024 Dec;
14(12).
PMID: 39727878
Bright biocompatible fluorescent imaging dyes with red to near-infrared (NIR) emissions are ideal candidates for fluorescence microscopy applications. Pyrene-benzothiazolium hemicyanine dyes are a new class of lysosome-specific probes reported on...
3.
Low J, Altman R, Badolian A, Cuaresma A, Briseno C, Keshet U, et al.
bioRxiv
. 2024 Dec;
PMID: 39713339
Heat shock protein A1A (HSPA1A) is a molecular chaperone crucial in cell survival. In addition to its cytosolic functions, HSPA1A translocates to heat-shocked and cancer cells' plasma membrane (PM). In...
4.
Dutta M, Dolan K, Amiar S, Bass E, Sultana R, Voth G, et al.
bioRxiv
. 2024 Nov;
PMID: 39574576
M is the most abundant structural membrane protein in coronaviruses and is essential for the formation of infectious virus particles. SARS-CoV-2 M adopts two conformations, M and M, and regulated...
5.
Sultana R, Stahelin R
Virology
. 2024 Nov;
601:110285.
PMID: 39536645
Virus-like particles (VLPs) resemble the parent virus but lack the viral genome, providing a safe and efficient platform for the analysis of virus assembly and budding as well as the...
6.
Amiar S, Johnson K, Husby M, Marzi A, Stahelin R
J Lipid Res
. 2024 Oct;
65(11):100663.
PMID: 39369791
Plasma membrane (PM) domains and order phases have been shown to play a key role in the assembly, release, and entry of several lipid-enveloped viruses. In the present study, we...
7.
Cioffi M, Sharma T, Motsa B, Bhattarai N, Gerstman B, Stahelin R, et al.
J Phys Chem B
. 2024 Sep;
128(46):11335-11344.
PMID: 39326870
Viral proteins frequently undergo single or multiple amino acid mutations during replication, which can significantly alter their functionality. The Ebola virus matrix protein VP40 is multifunctional but primarily responsible for...
8.
Sanford L, Keiser P, Fujii N, Woods H, Zhang C, Xu Z, et al.
Eur J Med Chem
. 2024 Jun;
275:116537.
PMID: 38875806
Diphyllin is a naturally occurring lignan comprised of an aryl naphthalene lactone scaffold that demonstrates beneficial biological activities in disease models of cancer, obesity, and viral infection. A target of...
9.
Dutta M, Su Y, Plescia C, Voth G, Stahelin R
J Biol Chem
. 2024 Jun;
300(8):107456.
PMID: 38866325
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a lipid-enveloped virus that acquires its lipid bilayer from the host cell it infects. SARS-CoV-2 can spread from cell to cell or...
10.
Impact of Ebola virus nucleoprotein on VP40 virus-like particle production: a computational approach
Liu X, Stahelin R, Pienaar E
Commun Biol
. 2024 May;
7(1):634.
PMID: 38796621
Ebola virus (EBOV) matrix protein VP40 can assemble and bud as virus-like particles (VLPs) when expressed alone in mammalian cells. Nucleoprotein (NP) could be recruited to VLPs as inclusion body...