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Robert E W Hancock

Explore the profile of Robert E W Hancock including associated specialties, affiliations and a list of published articles. Areas
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Articles 464
Citations 30106
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Recent Articles
1.
Pont S, Nilly F, Berry L, Bonhoure A, Alford M, Louis M, et al.
PLoS Pathog . 2025 Feb; 21(2):e1012922. PMID: 39946497
Persistent bacterial infections evade host immunity and resist antibiotic treatments through various mechanisms that are difficult to evaluate in a living host. Pseudomonas aeruginosa is a main cause of chronic...
2.
Wardell S, Yung D, Gupta A, Bostina M, Overhage J, Hancock R, et al.
NPJ Biofilms Microbiomes . 2025 Jan; 11(1):8. PMID: 39779734
Chronic infections represent a significant global health and economic challenge. Biofilms, which are bacterial communities encased in an extracellular polysaccharide matrix, contribute to approximately 80% of these infections. In particular,...
3.
An A, Acton E, Idoko O, Shannon C, Blimkie T, Falsafi R, et al.
EBioMedicine . 2024 Oct; 110:105411. PMID: 39472236
Background: Neonatal sepsis is a deadly disease with non-specific clinical signs, delaying diagnosis and treatment. There remains a need for early biomarkers to facilitate timely intervention. Our objective was to...
4.
Ho C, Wong C, Aung T, Lakshminarayanan R, Mehta J, Rauz S, et al.
Lancet Microbe . 2024 Sep; 6(1):100947. PMID: 39305919
Antimicrobial resistance (AMR) is a serious threat to global public health, with approximately 5 million deaths associated with bacterial AMR in 2019. Tackling AMR requires a multifaceted and cohesive approach...
5.
Martino D, Kresoje N, Amenyogbe N, Ben-Othman R, Cai B, Lo M, et al.
Nat Commun . 2024 Sep; 15(1):8167. PMID: 39289350
Understanding of newborn immune ontogeny in the first week of life will enable age-appropriate strategies for safeguarding vulnerable newborns against infectious diseases. Here we conducted an observational study exploring the...
6.
Blimkie T, An A, Hancock R
PLoS Comput Biol . 2024 Sep; 20(9):e1012422. PMID: 39283925
R package pathlinkR is designed to aid transcriptomic analyses by streamlining and simplifying the process of analyzing and interpreting differentially expressed genes derived from human RNA-Seq data. It provides an...
7.
Fidanza M, Hibbert J, Acton E, Harbeson D, Schoeman E, Skut P, et al.
Sci Rep . 2024 May; 14(1):11444. PMID: 38769383
Neonatal sepsis is a major cause of childhood mortality. Limited diagnostic tools and mechanistic insights have hampered our abilities to develop prophylactic or therapeutic interventions. Biomarkers in human neonatal sepsis...
8.
Esposito T, Blackadar C, Wu L, Rodriguez-Rodriguez C, Haney E, Pletzer D, et al.
Mol Pharm . 2024 May; 21(6):2751-2766. PMID: 38693707
Innate defense regulator-1002 (IDR-1002) is a synthetic peptide with promising immunomodulatory and antibiofilm properties. An appreciable body of work exists around its mechanism of action at the cellular and molecular...
9.
Dhillon B, Kortbeek S, Baghela A, Brindle M, Martin D, Jenne C, et al.
JAMA Pediatr . 2024 Feb; 178(4):391-400. PMID: 38372989
Importance: Appendicitis is the most common indication for urgent surgery in the pediatric population, presenting across a range of severity and with variable complications. Differentiating simple appendicitis (SA) and perforated...
10.
Wang D, Yue Y, Liu H, Zhang T, Haney E, Hancock R, et al.
Front Bioeng Biotechnol . 2024 Jan; 11:1339912. PMID: 38274010
Titanium alloys have gained popularity in implant dentistry for the restoration of missing teeth and related hard tissues because of their biocompatibility and enhanced strength. However, titanium corrosion and infection...