Robert Chenevert
Overview
Explore the profile of Robert Chenevert including associated specialties, affiliations and a list of published articles.
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21
Citations
140
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Recent Articles
1.
Pham V, Maaroufi H, Balg C, Blais S, Messier N, Roy P, et al.
FEBS Lett
. 2016 Sep;
590(19):3335-3345.
PMID: 27586694
Glutaminyl-tRNA in Helicobacter pylori is formed by an indirect route requiring a noncanonical glutamyl-tRNA synthetase and a tRNA-dependent heterotrimeric amidotransferase (AdT) GatCAB. Widespread use of this pathway among prominent human...
2.
Blais S, Kornblatt J, Barbeau X, Bonnaure G, Lague P, Chenevert R, et al.
PLoS One
. 2015 Jun;
10(6):e0130238.
PMID: 26039673
No abstract available.
3.
Blais S, Kornblatt J, Barbeau X, Bonnaure G, Lague P, Chenevert R, et al.
PLoS One
. 2015 Apr;
10(4):e0121043.
PMID: 25860020
For tRNA-dependent protein biosynthesis, amino acids are first activated by aminoacyl-tRNA synthetases (aaRSs) yielding the reaction intermediates aminoacyl-AMP (aa-AMP). Stable analogues of aa-AMP, such as aminoacyl-sulfamoyl-adenosines, inhibit their cognate aaRSs....
4.
Balg C, De Mieri M, Huot J, Blais S, Lapointe J, Chenevert R
Bioorg Med Chem
. 2010 Oct;
18(22):7868-72.
PMID: 20943400
Genomic studies revealed the absence of glutaminyl-tRNA synthetase and/or asparaginyl-tRNA synthetase in many bacteria and all known archaea. In these microorganisms, glutaminyl-tRNA(Gln) (Gln-tRNA(Gln)) and/or asparaginyl-tRNA(Asn) (Asn-tRNA(Asn)) are synthesized via an...
5.
Messmer M, Blais S, Balg C, Chenevert R, Grenier L, Lague P, et al.
Biochimie
. 2009 Mar;
91(5):596-603.
PMID: 19254750
Human mitochondrial aminoacyl-tRNA synthetases (mt-aaRSs), the enzymes which esterify tRNAs with the cognate specific amino acid, form mainly a different set of proteins than those involved in the cytosolic translation...
6.
Chenevert R, Morin P
Bioorg Med Chem
. 2009 Feb;
17(5):1837-9.
PMID: 19217305
The bioactive alkaloid (-)-lobeline was synthesized via the stereoselective acylation (desymmetrization) of meso-lobelanidine by vinyl acetate in the presence of Candida antarctica lipase B.
7.
Paravisi S, Fumagalli G, Riva M, Morandi P, Morosi R, Konarev P, et al.
FEBS J
. 2009 Feb;
276(5):1398-417.
PMID: 19187240
Mycobacterium tuberculosis glutamyl-tRNA synthetase (Mt-GluRS), encoded by Rv2992c, was overproduced in Escherichia coli cells, and purified to homogeneity. It was found to be similar to the other well-characterized GluRS, especially...
8.
Chenevert R, Levesque C, Morin P
J Org Chem
. 2008 Nov;
73(23):9501-3.
PMID: 18991382
The stereoselective acetylation of meso-2,2-dimethyl-1,3-cyclohexanediol by vinyl acetate in the presence of three lipases gave the (1R,3S)-monoester in high enantiomeric excess (ee > or = 98%). The hydrolysis of the...
9.
Balg C, Huot J, Lapointe J, Chenevert R
J Am Chem Soc
. 2008 Feb;
130(11):3264-5.
PMID: 18293984
No abstract available.
10.
Huot J, Balg C, Jahn D, Moser J, Emond A, Blais S, et al.
Biochemistry
. 2007 Oct;
46(45):13190-8.
PMID: 17929881
The trimeric GatCAB aminoacyl-tRNA amidotransferases catalyze the amidation of Asp-tRNAAsn and/or Glu-tRNAGln to Asn-tRNAAsn and/or Gln-tRNAGln, respectively, in bacteria and archaea lacking an asparaginyl-tRNA synthetase and/or a glutaminyl-tRNA synthetase. The...