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Richard P Mayeux

Explore the profile of Richard P Mayeux including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 1509
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Recent Articles
11.
Kang M, Ang T, Devine S, Sherva R, Mukherjee S, Trittschuh E, et al.
Mol Neurodegener . 2023 Jun; 18(1):40. PMID: 37349795
Background: More than 75 common variant loci account for only a portion of the heritability for Alzheimer's disease (AD). A more complete understanding of the genetic basis of AD can...
12.
Yang H, Teng L, Kang D, Menon V, Ge T, Finucane H, et al.
medRxiv . 2023 Jun; PMID: 37333223
Alzheimer's disease (AD) heritability is enriched in glial genes, but how and when cell-type-specific genetic risk contributes to AD remains unclear. Here, we derive cell-type-specific AD polygenic risk scores (ADPRS)...
13.
Ali M, Archer D, Gorijala P, Western D, Timsina J, Fernandez M, et al.
Acta Neuropathol Commun . 2023 Apr; 11(1):68. PMID: 37101235
Amyloid PET imaging has been crucial for detecting the accumulation of amyloid beta (Aβ) deposits in the brain and to study Alzheimer's disease (AD). We performed a genome-wide association study...
14.
Rajabli F, Tosto G, Hamilton-Nelson K, Kunkle B, Vardarajan B, Naj A, et al.
Alzheimers Dement . 2022 Dec; 19(6):2538-2548. PMID: 36539198
Background: This study used admixture mapping to prioritize the genetic regions associated with Alzheimer's disease (AD) in African American (AA) individuals, followed by ancestry-aware regression analysis to fine-map the prioritized...
15.
Chapman S, Arce Renteria M, Dworkin J, Garriga S, Barker M, Avila-Rieger J, et al.
Neurology . 2022 Nov; 100(10):e1020-e1027. PMID: 36450605
Background And Objectives: This prospective study seeks to examine the utility of subjective cognitive decline (SCD) as a marker of future progression to dementia in a community-based cohort of non-Latinx...
16.
Ramos J, Caywood L, Prough M, Clouse J, Herington S, Slifer S, et al.
Alzheimers Dement . 2022 May; 19(2):611-620. PMID: 35490390
Introduction: Studies of cognitive impairment (CI) in Amish communities have identified sibships containing CI and cognitively unimpaired (CU) individuals. We hypothesize that CU individuals may carry protective alleles delaying age...
17.
Shade L, Katsumata Y, Hohman T, Nho K, Saykin A, Mukherjee S, et al.
J Cereb Blood Flow Metab . 2022 Feb; 42(8):1437-1450. PMID: 35156446
Brain arteriolosclerosis (B-ASC) is characterized by pathologically altered brain parenchymal arterioles. B-ASC is associated with cognitive impairment and increased likelihood of clinical dementia. To date, no study has been conducted...
18.
Guo J, Schupf N, Cruz E, Stern Y, Mayeux R, Gu Y
J Gerontol A Biol Sci Med Sci . 2022 Jan; 77(9):1873-1881. PMID: 35029675
Background: Current evidence on the association between Mediterranean diet (MeDi) intake and activities of daily living (ADL) is limited and inconsistent in older adults. Methods: This study included 1 696...
19.
Nishikawa M, Brickman A, Manly J, Schupf N, Mayeux R, Gu Y
Curr Alzheimer Res . 2021 Dec; 18(12):984-992. PMID: 34951365
Objective: This study aimed to investigate the association between dietary prebiotic intake and risk for Alzheimer's disease (AD). Methods: This longitudinal study includes 1,837 elderly (≥65 years) participants of a...
20.
Guo J, Brickman A, Manly J, Reitz C, Schupf N, Mayeux R, et al.
Alzheimers Dement . 2021 May; 17(12):1905-1913. PMID: 33938146
Introduction: There is limited and inconsistent reporting on the association between Life's Simple 7 (LS7) and dementia in the elderly population. Methods: Based on the Washington Heights-Inwood Columbia Aging Project...