Richard M Weinshilboum
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Explore the profile of Richard M Weinshilboum including associated specialties, affiliations and a list of published articles.
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204
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5171
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Recent Articles
21.
Nguyen T, Wang M, Liu D, Iyer S, Gonzalez Bonilla H, Acker N, et al.
Circ Heart Fail
. 2022 Jun;
15(9):e009629.
PMID: 35656806
No abstract available.
22.
Fasching P, Liu D, Scully S, Ingle J, Lyra P, Rack B, et al.
Clin Cancer Res
. 2022 Jun;
28(15):3342-3355.
PMID: 35653140
Purpose: To identify molecular predictors of grade 3/4 neutropenic or leukopenic events (NLE) after chemotherapy using a genome-wide association study (GWAS). Experimental Design: A GWAS was performed on patients in...
23.
Wang L, Scherer S, Bielinski S, Muzny D, Jones L, Black 3rd J, et al.
Genet Med
. 2022 Mar;
24(5):1062-1072.
PMID: 35331649
Purpose: The Mayo-Baylor RIGHT 10K Study enabled preemptive, sequence-based pharmacogenomics (PGx)-driven drug prescribing practices in routine clinical care within a large cohort. We also generated the tools and resources necessary...
24.
Qin S, Gao H, Kim W, Zhang H, Gu Y, Kalari K, et al.
Clin Pharmacol Ther
. 2022 Mar;
111(6):1296-1306.
PMID: 35288936
Approximately one-third of patients with metastatic castration-resistant prostate cancer (CRPC) exhibited primary abiraterone resistance. To identify alternative treatment for abiraterone nonresponders, we performed drug discovery analyses using the L1000 database...
25.
Athreya A, Vande Voort J, Shekunov J, Rackley S, Leffler J, McKean A, et al.
J Child Psychol Psychiatry
. 2022 Mar;
63(11):1347-1358.
PMID: 35288932
Background: The treatment of depression in children and adolescents is a substantial public health challenge. This study examined artificial intelligence tools for the prediction of early outcomes in depressed children...
26.
Peddi P, Fasching P, Liu D, Quinaux E, Robert N, Valero V, et al.
Clin Cancer Res
. 2022 Feb;
28(9):1854-1862.
PMID: 35110416
Purpose: Cardiac toxicity is a serious potential complication of HER2-directed therapies and anthracyclines. HER2 codon 655 and SLC28A3 gene polymorphisms have been reported to be associated with cardiac toxicity from...
27.
Lopes J, Harris K, Karow M, Peterson S, Kluge M, Kotzer K, et al.
J Mol Diagn
. 2022 Jan;
24(3):253-261.
PMID: 35041929
Clinical pharmacogenomic testing typically uses targeted genotyping, which only detects variants included in the test design and may vary among laboratories. To evaluate the potential patient impact of genotyping compared...
28.
Ho M, Zhang C, Wei L, Zhang L, Moon I, Geske J, et al.
Br J Pharmacol
. 2022 Jan;
179(13):3330-3345.
PMID: 35016259
Background And Purpose: Acamprosate is an anti-craving drug used for the pharmacotherapy of alcohol use disorder (AUD). However, only some patients achieve optimal therapeutic outcomes. This study was designed to...
29.
Myasoedova E, Athreya A, Crowson C, Davis 3rd J, Warrington K, Walchak R, et al.
Arthritis Care Res (Hoboken)
. 2021 Dec;
74(6):879-888.
PMID: 34902228
Objective: To test the ability of machine learning (ML) approaches with clinical and genomic biomarkers to predict methotrexate treatment response in patients with early rheumatoid arthritis (RA). Methods: Demographic, clinical,...
30.
Cairns J, Ingle J, Kalari K, Goetz M, Weinshilboum R, Gao H, et al.
Mol Cancer Ther
. 2021 Oct;
21(1):206-216.
PMID: 34667110
Our previous matched case-control study of postmenopausal women with resected early-stage breast cancer revealed that only anastrozole, but not exemestane or letrozole, showed a significant association between the 6-month estrogen...