Richard G Hibbert
Overview
Explore the profile of Richard G Hibbert including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
598
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0
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Recent Articles
11.
Hibbert R, Huang A, Boelens R, Sixma T
Proc Natl Acad Sci U S A
. 2011 Mar;
108(14):5590-5.
PMID: 21422291
In ubiquitin conjugation, different combinations of E2 and E3 enzymes catalyse either monoubiquitination or ubiquitin chain formation. The E2/E3 complex Rad6/Rad18 exclusively monoubiquitinates the proliferating cell nuclear antigen (PCNA) to...
12.
Bienko M, Green C, Sabbioneda S, Crosetto N, Matic I, Hibbert R, et al.
Mol Cell
. 2010 Feb;
37(3):396-407.
PMID: 20159558
DNA polymerase eta is a Y family polymerase involved in translesion synthesis (TLS). Its action is initiated by simultaneous interaction between the PIP box in pol eta and PCNA and...
13.
Hibbert R, Mattiroli F, Sixma T
DNA Repair (Amst)
. 2009 Mar;
8(4):525-35.
PMID: 19249250
Ubiquitin conjugation plays critical roles in virtually all DNA repair pathways. This review provides an overview of the known multi-domain RING/Ubox E3 ligases and their domain structures. An analysis of...
14.
Crosetto N, Bienko M, Hibbert R, Perica T, Ambrogio C, Kensche T, et al.
J Biol Chem
. 2008 Oct;
283(50):35173-85.
PMID: 18842586
Wrnip1 (Werner helicase-interacting protein 1) has been implicated in the bypass of stalled replication forks in bakers' yeast. However, the function(s) of human Wrnip1 has remained elusive so far. Here...
15.
Notenboom V, Hibbert R, van Rossum-Fikkert S, Olsen J, Mann M, Sixma T
Nucleic Acids Res
. 2007 Aug;
35(17):5819-30.
PMID: 17720710
Rad18 is a ubiquitin E3 ligase that monoubiquitinates PCNA on stalled replications forks. This allows recruitment of damage-tolerant polymerases for damage bypass and DNA repair. In this activity, the Rad18...
16.
Hibbert R, Teriete P, Grundy G, Beavil R, Reljic R, Holers V, et al.
J Exp Med
. 2005 Sep;
202(6):751-60.
PMID: 16172256
The low-affinity immunoglobulin E (IgE) receptor, CD23 (FcepsilonRII), binds both IgE and CD21 and, through these interactions, regulates the synthesis of IgE, the antibody isotype that mediates the allergic response....
17.
Butler M, Quelhas D, Critchley A, Carchon H, Hebestreit H, Hibbert R, et al.
Glycobiology
. 2003 May;
13(9):601-22.
PMID: 12773475
The fundamental importance of correct protein glycosylation is abundantly clear in a group of diseases known as congenital disorders of glycosylation (CDGs). In these diseases, many biological functions are compromised,...