Reinier A Boon
Overview
Explore the profile of Reinier A Boon including associated specialties, affiliations and a list of published articles.
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103
Citations
5496
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Recent Articles
1.
Liberale L, Tual-Chalot S, Sedej S, Ministrini S, Georgiopoulos G, Grunewald M, et al.
Nat Rev Cardiol
. 2025 Feb;
PMID: 39972009
Ageing of the cardiovascular system is associated with frailty and various life-threatening diseases. As global populations grow older, age-related conditions increasingly determine healthspan and lifespan. The circulatory system not only...
2.
Maji R, Leisegang M, Boon R, Schulz M
Trends Genet
. 2025 Jan;
PMID: 39863489
MicroRNAs (miRNAs) are key regulators of gene expression and control cellular functions in physiological and pathophysiological states. miRNAs play important roles in disease, stress, and development, and are now being...
3.
Yuan Q, Verbueken D, Dinani R, Kim R, Schoger E, Morsink C, et al.
Stem Cell Reports
. 2024 Dec;
20(1):102371.
PMID: 39642876
Embryonic signaling pathways exert stage-specific effects during cardiac development, yet the precise signals for proliferation or maturation remain elusive. To uncover the cues for proliferation, we performed a combinatory cell-cycle...
4.
Woudenberg T, van der Bent M, Kremer V, Waas I, Daemen M, Boon R, et al.
Br J Pharmacol
. 2024 Oct;
PMID: 39419283
Background And Purpose: Intracranial atherosclerosis is one of the most common causes of ischaemic stroke. However, there is a substantial knowledge gap on the development of intracranial atherosclerosis. Intracranial arteries...
5.
Lozano-Vidal N, Stanicek L, Bink D, Juni R, Hooglugt A, Kremer V, et al.
Commun Biol
. 2024 May;
7(1):541.
PMID: 38714838
Age-related diseases pose great challenges to health care systems worldwide. During aging, endothelial senescence increases the risk for cardiovascular disease. Recently, it was described that Phosphatase 1 Nuclear Targeting Subunit...
6.
Hooglugt A, van der Stoel M, Shapeti A, Neep B, de Haan A, Van Oosterwyck H, et al.
J Cell Sci
. 2024 Apr;
137(8).
PMID: 38563084
Angiogenesis is a tightly controlled dynamic process demanding a delicate equilibrium between pro-angiogenic signals and factors that promote vascular stability. The spatiotemporal activation of the transcriptional co-factors YAP (herein referring...
7.
de Winter J, Molenaar J, Yuen M, van der Pijl R, Shen S, Conijn S, et al.
J Clin Invest
. 2024 Feb;
134(3).
PMID: 38299595
No abstract available.
8.
Tammaro A, Daniels E, Hu I, t Hart K, Reid K, Juni R, et al.
iScience
. 2024 Jan;
27(1):108681.
PMID: 38269100
Aging increases the risk of age-related diseases, imposing substantial healthcare and personal costs. Targeting fundamental aging mechanisms pharmacologically can promote healthy aging and reduce this disease susceptibility. In this work,...
9.
Jalink E, Schonk A, Boon R, Juni R
Front Cardiovasc Med
. 2024 Jan;
10:1300375.
PMID: 38259314
Heart failure with preserved ejection fraction (HFpEF) is the largest unmet clinical need in cardiovascular medicine. Despite decades of research, the treatment option for HFpEF is still limited, indicating our...
10.
Maegdefessel L, Boon R, Dimmeler S
Arterioscler Thromb Vasc Biol
. 2023 Dec;
44(1):3-6.
PMID: 38150514
No abstract available.