Reina N Fuji
Overview
Explore the profile of Reina N Fuji including associated specialties, affiliations and a list of published articles.
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26
Citations
1195
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Recent Articles
1.
Zehnder P, Feng J, Nguyen T, Shen P, Sullivan R, Fuji R, et al.
Sci Rep
. 2025 Feb;
15(1):4202.
PMID: 39905121
The diagnostic classification of digitized tissue images based on histopathologic lesions present in whole slide images (WSI) is a significant task that eludes modern image classification techniques. Even with advanced...
2.
Shelton A, Schutten M, Fuji R, Boyd R, Stevenson V, Leahy M, et al.
Retina
. 2025 Jan;
PMID: 39778117
Purpose: To evaluate an alternative surgical approach for Port Delivery System with ranibizumab (PDS) implant and a novel application of Iridex laser system in Gottingen minipig model. Methods: A total...
3.
Schauer S, Cho C, Novikova G, Roth G, Lee J, Sharma A, et al.
Alzheimers Dement
. 2024 Aug;
20(9):5861-5888.
PMID: 39090679
Introduction: Triggering receptor expressed on myeloid cells 2 (TREM2) agonists are being clinically evaluated as disease-modifying therapeutics for Alzheimer's disease. Clinically translatable pharmacodynamic (PD) biomarkers are needed to confirm drug...
4.
Chu M, Ge X, Eastham J, Nguyen T, Fuji R, Sullivan R, et al.
Toxicol Pathol
. 2024 Jan;
51(6):313-328.
PMID: 38288712
Digital pathology workflows in toxicologic pathology rely on whole slide images (WSIs) from histopathology slides. Inconsistent color reproduction by WSI scanners of different models and from different manufacturers can result...
5.
Shiffman S, Rios Piedra E, Adedeji A, Ruff C, Andrews R, Katavolos P, et al.
J Pathol Inform
. 2023 Sep;
14:100333.
PMID: 37743975
Our objective was to develop an automated deep-learning-based method to evaluate cellularity in rat bone marrow hematoxylin and eosin whole slide images for preclinical safety assessment. We trained a shallow...
6.
Ge X, Funk J, Albrecht T, Birkhimer M, Gilsdorf M, Hayes M, et al.
Toxicol Pathol
. 2022 Nov;
50(8):942-949.
PMID: 36341579
Digitization of histologic slides brings with it the promise of enhanced toxicologic pathology practice through the increased application of computational methods. However, the development of these advanced methods requires access...
7.
Ramakrishnan V, Friedrich C, Witt C, Sheehan R, Pryor M, Atwal J, et al.
CPT Pharmacometrics Syst Pharmacol
. 2022 Oct;
12(1):62-73.
PMID: 36281062
Despite considerable investment into potential therapeutic approaches for Alzheimer's disease (AD), currently approved treatment options are limited. Predictive modeling using quantitative systems pharmacology (QSP) can be used to guide the...
8.
Zehnder P, Feng J, Fuji R, Sullivan R, Hu F
J Pathol Inform
. 2022 Oct;
13:100102.
PMID: 36268071
Background: Automated anomaly detection is an important tool that has been developed for many real-world applications, including security systems, industrial inspection, and medical diagnostics. Despite extensive use of machine learning...
9.
Teng E, Manser P, Pickthorn K, Brunstein F, Blendstrup M, Sanabria Bohorquez S, et al.
JAMA Neurol
. 2022 Jun;
79(8):758-767.
PMID: 35696185
Importance: Neurofibrillary tangles composed of aggregated tau protein are one of the neuropathological hallmarks of Alzheimer disease (AD) and correlate with clinical disease severity. Monoclonal antibodies targeting tau may have...
10.
Sadekar S, Bowen M, Cai H, Jamalian S, Rafidi H, Shatz-Binder W, et al.
Clin Pharmacol Ther
. 2022 Jan;
111(4):826-834.
PMID: 35064573
Delivery of biologics via cerebrospinal fluid (CSF) has demonstrated potential to access the tissues of the central nervous system (CNS) by circumventing the blood-brain barrier and blood-CSF barrier. Developing an...