Raul M Goldschmidt
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Explore the profile of Raul M Goldschmidt including associated specialties, affiliations and a list of published articles.
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5
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39
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Recent Articles
1.
Wiener J, Gomez L, Venkatesan H, Santillan Jr A, Allison B, Schwarz K, et al.
Bioorg Med Chem Lett
. 2007 Mar;
17(10):2718-22.
PMID: 17382544
We have previously reported a novel class of tetrahydroindazoles that display potency against a variety of Gram-positive and Gram-negative bacteria, potentially via interaction with type II bacterial topoisomerases. Herein are...
2.
Foleno B, Abbanat D, Goldschmidt R, Flamm R, Paget S, Webb G, et al.
Antimicrob Agents Chemother
. 2006 Nov;
51(1):361-5.
PMID: 17101672
RWJ-416457, an investigational pyrrolopyrazolyl-substituted oxazolidinone, inhibited the growth of linezolid-susceptible staphylococci, enterococci, and streptococci at concentrations of < or =4 microg/ml, generally exhibiting two- to fourfold-greater potency than that of...
3.
Paget S, Boggs C, Foleno B, Goldschmidt R, Hlasta D, Weidner-Wells M, et al.
Bioorg Med Chem Lett
. 2006 Jun;
16(17):4537-42.
PMID: 16806921
A series of pyrrolopyridine-substituted oxazolidinones containing various C-5 acetamide isosteres was synthesized and the structure-antibacterial activity relationships determined against a representative panel of susceptible and resistant Gram-positive bacteria.
4.
Paget S, Foleno B, Boggs C, Goldschmidt R, Hlasta D, Weidner-Wells M, et al.
Bioorg Med Chem Lett
. 2003 Nov;
13(23):4173-7.
PMID: 14622996
A novel series of oxazolidinones containing a pyrroloaryl substituent was synthesized and screened against a representative panel of susceptible and resistant Gram-positive bacteria. Several members of this series were found...
5.
Weidner-Wells M, Boggs C, Foleno B, Melton J, Bush K, Goldschmidt R, et al.
Bioorg Med Chem
. 2002 May;
10(7):2345-51.
PMID: 11983532
Oxazolidinone antibacterial agents, where the morpholino group of linezolid was replaced with an N-substituted piperidinyloxy moiety, were synthesized and shown to be active against a variety of resistant and susceptible...