Rashna Bhandari
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Explore the profile of Rashna Bhandari including associated specialties, affiliations and a list of published articles.
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35
Citations
884
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Recent Articles
21.
Thota S, Bhandari R
J Biosci
. 2015 Sep;
40(3):593-605.
PMID: 26333405
Inositol pyrophosphates are water soluble derivatives of inositol that contain pyrophosphate or diphosphate moieties in addition to monophosphates. The best characterised inositol pyrophosphates, are IP7 (diphosphoinositol pentakisphosphate or PP-IP5), and...
22.
Thota S, Unnikannan C, Thampatty S, Manorama R, Bhandari R
Biochem J
. 2014 Nov;
466(1):105-14.
PMID: 25423617
Ribosome biogenesis is an essential cellular process regulated by the metabolic state of a cell. We examined whether inositol pyrophosphates, energy-rich derivatives of inositol that act as metabolic messengers, play...
23.
Ghosh S, Shukla D, Suman K, Lakshmi B, Manorama R, Kumar S, et al.
Blood
. 2013 Jun;
122(8):1478-86.
PMID: 23782934
Polyphosphate (polyP), a polymer of orthophosphate moieties released from the dense granules of activated platelets, is a procoagulant agent. Inositol pyrophosphates, another group of phosphate-rich molecules, consist of mono- and...
24.
Jadav R, Chanduri M, Sengupta S, Bhandari R
J Biol Chem
. 2012 Dec;
288(5):3312-21.
PMID: 23255604
Inositol pyrophosphates, such as diphosphoinositol pentakisphosphate (IP(7)), are water-soluble inositol phosphates that contain high energy diphosphate moieties on the inositol ring. Inositol hexakisphosphate kinase 1 (IP6K1) participates in inositol pyrophosphate...
25.
Werner Jr J, Speed T, Bhandari R
Methods Mol Biol
. 2010 Jul;
645:87-102.
PMID: 20645183
Diphosphoinositol polyphosphates, also known as inositol pyrophosphates, are a family of water soluble inositol phosphates that possess diphosphate or pyrophosphate moieties. In the presence of divalent cations such as Mg(2+),...
26.
Basu N, Bhandari R, Natarajan V, Visweswariah S
Mol Cell Biol
. 2009 Jul;
29(19):5277-89.
PMID: 19620276
Increased activation of c-src seen in colorectal cancer is an indicator of a poor clinical prognosis, suggesting that identification of downstream effectors of c-src may lead to new avenues of...
27.
Ponnusamy S, Alderson N, Hama H, Bielawski J, Jiang J, Bhandari R, et al.
J Biol Chem
. 2008 Aug;
283(41):27514-27524.
PMID: 18694931
In this study, we investigated the roles of very long-chain fatty acid (VLCFA) synthesis by fatty acid elongase 3 (ELO3) in the regulation of telomere length and life span in...
28.
Draskovic P, Saiardi A, Bhandari R, Burton A, Ilc G, Kovacevic M, et al.
Chem Biol
. 2008 Mar;
15(3):274-86.
PMID: 18355727
Eukaryotic cells produce a family of diverse inositol polyphosphates (IPs) containing pyrophosphate bonds. Inositol pyrophosphates have been linked to a wide range of cellular functions, and there is growing evidence...
29.
Bhandari R, Juluri K, Resnick A, Snyder S
Proc Natl Acad Sci U S A
. 2008 Feb;
105(7):2349-53.
PMID: 18268345
Inositol pyrophosphates, also designated inositol diphosphates, possess high-energy beta-phosphates that can pyrophosphorylate proteins and regulate various cellular processes. They are formed by a family of inositol hexakisphosphate kinases (IP6Ks). We...
30.
Bhandari R, Saiardi A, Ahmadibeni Y, Snowman A, Resnick A, Kristiansen T, et al.
Proc Natl Acad Sci U S A
. 2007 Sep;
104(39):15305-10.
PMID: 17873058
In a previous study, we showed that the inositol pyrophosphate diphosphoinositol pentakisphosphate (IP(7)) physiologically phosphorylates mammalian and yeast proteins. We now report that this phosphate transfer reflects pyrophosphorylation. Thus, proteins...