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Shubhra Ganguli

Explore the profile of Shubhra Ganguli including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 82
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Recent Articles
1.
Hamid A, Ladke J, Shah A, Ganguli S, Pal M, Singh A, et al.
Biosci Rep . 2024 Sep; 44(10). PMID: 39230924
Inositol pyrophosphates (PP-InsPs) are a sub-family of water soluble inositol phosphates that possess one or more diphosphate groups. PP-InsPs can transfer their β-phosphate group to a phosphorylated Ser residue to...
2.
Morgan J, Singh A, Kurz L, Nadler-Holly M, Ruwolt M, Ganguli S, et al.
Nat Chem Biol . 2024 Apr; 20(10):1305-1316. PMID: 38664588
Reversible protein phosphorylation is a central signaling mechanism in eukaryotes. Although mass-spectrometry-based phosphoproteomics has become routine, identification of non-canonical phosphorylation has remained a challenge. Here we report a tailored workflow...
3.
Shukla A, Kaur M, Kanwar S, Kaur G, Sharma S, Ganguli S, et al.
BMC Biol . 2021 Dec; 19(1):261. PMID: 34895221
Background: Inositol pyrophosphates (PP-InsPs) are high-energy derivatives of inositol, involved in different signalling and regulatory responses of eukaryotic cells. Distinct PP-InsPs species are characterized by the presence of phosphate at...
4.
Mohanrao R, Manorama R, Ganguli S, Madhusudhanan M, Bhandari R, Sureshan K
Molecules . 2021 Jul; 26(12). PMID: 34208421
IP6K and PPIP5K are two kinases involved in the synthesis of inositol pyrophosphates. Synthetic analogs or mimics are necessary to understand the substrate specificity of these enzymes and to find...
5.
Shah A, Ganguli S, Sen J, Bhandari R
J Indian Inst Sci . 2020 Mar; 97(1):23-40. PMID: 32214696
Inositol pyrophosphates (PP-IPs) are a class of energy-rich signalling molecules found in all eukaryotic cells. These are derivatives of inositol that contain one or more diphosphate (or pyrophosphate) groups in...
6.
Ganguli S, Shah A, Hamid A, Singh A, Palakurti R, Bhandari R
Adv Biol Regul . 2019 Nov; 75():100662. PMID: 31668836
Inositol pyrophosphates (PP-IPs) are a class of energy rich metabolites present in all eukaryotic cells. The hydroxyl groups on these water soluble derivatives of inositol are substituted with diphosphate and...
7.
Deota S, Rathnachalam S, Namrata K, Boob M, Fulzele A, Radhika S, et al.
J Mol Biol . 2019 Apr; 431(11):2127-2142. PMID: 30974121
Cyclin-dependent kinase 1 (CDK1) is essential for cell-cycle progression. While dependence of CDK activity on cyclin levels is well established, molecular mechanisms that regulate their binding are less understood. Here,...
8.
Jadav R, Kumar D, Buwa N, Ganguli S, Thampatty S, Balasubramanian N, et al.
Cell Signal . 2016 May; 28(8):1124-36. PMID: 27140681
Inositol hexakisphosphate kinases (IP6Ks), a family of enzymes found in all eukaryotes, are responsible for the synthesis of 5-diphosphoinositol pentakisphosphate (5-IP7) from inositol hexakisphosphate (IP6). Three isoforms of IP6Ks are...