R D Schreiber
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Explore the profile of R D Schreiber including associated specialties, affiliations and a list of published articles.
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186
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13460
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Recent Articles
1.
Fehlings M, Simoni Y, Penny H, Becht E, Loh C, Gubin M, et al.
Nat Commun
. 2018 Jul;
9(1):3000.
PMID: 30050138
The original version of this Article omitted a declaration from the competing interests statement, which should have included the following: 'R.D.S. is a cofounder, stock holder, and scientific advisory board...
2.
Fehlings M, Simoni Y, Penny H, Becht E, Loh C, Gubin M, et al.
Nat Commun
. 2017 Sep;
8(1):562.
PMID: 28916749
The analysis of neoantigen-specific CD8 T cells in tumour-bearing individuals is challenging due to the small pool of tumour antigen-specific T cells. Here we show that mass cytometry with multiplex...
3.
Chan S, Rickert C, Vermi W, Sheehan K, Arthur C, Allen J, et al.
Cell Death Differ
. 2013 Sep;
21(2):234-46.
PMID: 24037089
We previously reported that STAT1 expression is frequently abrogated in human estrogen receptor-α-positive (ERα(+)) breast cancers and mice lacking STAT1 spontaneously develop ERα(+) mammary tumors. However, the precise mechanism by...
4.
Schreiber R
Curr Protoc Immunol
. 2008 Apr;
Chapter 6:Unit 6.8.
PMID: 18432821
This unit describes two protocols that can be used to quantitate interferon gamma (IFN-gamma), an important modulatory lymphokine that regulates natural, cell-mediated, and humoral immunity by eliciting a number of...
5.
Strobl B, Arulampalam V, Isharc H, Newman S, Schlaak J, Watling D, et al.
EMBO J
. 2001 Sep;
20(19):5431-42.
PMID: 11574475
A tripartite receptor comprising the external region of the erythropoietin (Epo) receptor, the transmembrane and JAK-binding domains of the gp130 subunit of the interleukin-6 (IL-6) receptor, and a seven amino...
6.
Luker K, Pica C, Schreiber R, Piwnica-Worms D
Cancer Res
. 2001 Aug;
61(17):6540-7.
PMID: 11522652
IRF9/p48/ISGF3gamma (IRF9) is an IFN regulatory factor that mediates signaling by type I IFNs (IFNalpha and IFNbeta). After single-step selection of breast adenocarcinoma cells in paclitaxel, differential display and single...
7.
Dupuis S, Dargemont C, Fieschi C, Thomassin N, Rosenzweig S, Harris J, et al.
Science
. 2001 Jul;
293(5528):300-3.
PMID: 11452125
Interferons (IFN) alpha/beta and gamma induce the formation of two transcriptional activators: gamma-activating factor (GAF) and interferon-stimulated gamma factor 3 (ISGF3). We report a natural heterozygous germline STAT1 mutation associated...
8.
Gil M, Bohn E, OGuin A, Ramana C, Levine B, Stark G, et al.
Proc Natl Acad Sci U S A
. 2001 Jun;
98(12):6680-5.
PMID: 11390995
Although Stat1 is required for many IFN-dependent responses, recent work has shown that IFNgamma functions independently of Stat1 to affect the growth of tumor cells or immortalized fibroblasts. We now...
9.
Ramana C, Gil M, Han Y, Ransohoff R, Schreiber R, Stark G
Proc Natl Acad Sci U S A
. 2001 Jun;
98(12):6674-9.
PMID: 11390994
Although Stat1 is essential for cells to respond fully to IFN-gamma, there is substantial evidence that, in the absence of Stat1, IFN-gamma can still regulate the expression of some genes,...
10.
Shankaran V, Ikeda H, Bruce A, White J, Swanson P, Old L, et al.
Nature
. 2001 Apr;
410(6832):1107-11.
PMID: 11323675
Lymphocytes were originally thought to form the basis of a 'cancer immunosurveillance' process that protects immunocompetent hosts against primary tumour development, but this idea was largely abandoned when no differences...