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A S Dighe

Explore the profile of A S Dighe including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 1818
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Recent Articles
1.
Kratz A, Soderberg B, Szczepiorkowski Z, Dighe A, Versalovic J, Laposata M
Am J Clin Pathol . 2002 May; 116 Suppl:S133-40. PMID: 11993699
The logistical details for organizing effective interpretive rounds in a laboratory medicine subspecialty must be carefully established so that expert opinions are provided in a timely fashion in a patient-specific...
2.
Dighe A, Soderberg B, Laposata M
Am J Clin Pathol . 2002 May; 116 Suppl:S123-8. PMID: 11993697
As the clinical laboratory test menu has significantly expanded in volume and complexity, there is a rapidly growing need by clinicians for narrative interpretations of complex studies that resemble those...
3.
Dighe A, Shouche Y, Ranade D
Int J Syst Bacteriol . 1998 Sep; 48 Pt 3:783-91. PMID: 9734032
A novel, oligately anaerobic bacterium capable of hydrolysing lipids was isolated from a tropical anaerobic lagoon receiving waste water from an edible oil mill. The isolate had many characteristics similar...
4.
Kaplan D, Shankaran V, Dighe A, STOCKERT E, Aguet M, Old L, et al.
Proc Natl Acad Sci U S A . 1998 Jun; 95(13):7556-61. PMID: 9636188
This study demonstrates that endogenously produced interferon gamma (IFN-gamma) forms the basis of a tumor surveillance system that controls development of both chemically induced and spontaneously arising tumors in mice....
5.
Szabo S, Dighe A, Gubler U, Murphy K
J Exp Med . 1997 Mar; 185(5):817-24. PMID: 9120387
The developmental commitment to a T helper 1 (Th1)- or Th2-type response can significantly influence host immunity to pathogens. Extinction of the IL-12 signaling pathway during early Th2 development provides...
6.
Meraz M, White J, Sheehan K, Bach E, Rodig S, Dighe A, et al.
Cell . 1996 Feb; 84(3):431-42. PMID: 8608597
The JAK-STAT signaling pathway has been implicated in mediating biological responses induced by many cytokines. However, cytokines that promote distinct cellular responses often activate identical STAT proteins, thereby raising the...
7.
Bach E, Szabo S, Dighe A, Ashkenazi A, Aguet M, Murphy K, et al.
Science . 1995 Nov; 270(5239):1215-8. PMID: 7502050
Interferon gamma (IFN-gamma) responsiveness in certain cells depends on the state of cellular differentiation or activation. Here an in vitro developmental system was used to show that IFN-gamma produced during...
8.
Dighe A, Campbell D, Hsieh C, Clarke S, Greaves D, Gordon S, et al.
Immunity . 1995 Nov; 3(5):657-66. PMID: 7584155
The ubiquitous cellular distribution of certain cytokine receptors has hampered attempts to define the physiologically important cell-specific functions of cytokines in vivo. Herein, we report the generation of transgenic mice...
9.
Szabo S, Jacobson N, Dighe A, Gubler U, Murphy K
Immunity . 1995 Jun; 2(6):665-75. PMID: 7796298
Developmental-commitment to Th1 or Th2 responses critically influences host susceptibility to particular pathogens. We describe a novel mechanism governing stable commitment to Th2 differentiation. Naive T cells develop strongly polarized...
10.
Dighe A, Richards E, Old L, Schreiber R
Immunity . 1994 Sep; 1(6):447-56. PMID: 7895156
Using a neutralizing monoclonal antibody specific for murine IFN gamma we show that endogenously produced IFN gamma plays an obligate role in mediating LPS-induced rejection of the Meth A fibrosarcoma...