R D Polakiewicz
Overview
Explore the profile of R D Polakiewicz including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
1275
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0
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Recent Articles
1.
Zhang P, Guo A, Possemato A, Wang C, Beard L, Carlin C, et al.
Oncogene
. 2012 Jun;
32(16):2087-95.
PMID: 22710723
Protein tyrosine phosphatase nonreceptor type 14 (PTPN14) is frequently mutated in a variety of human cancers. However, the cell signaling pathways regulated by PTPN14 largely remain to be elucidated. Here,...
2.
Gu T, Cherry J, Tucker M, Wu J, Reeves C, Polakiewicz R
Leukemia
. 2010 Jan;
24(4):861-5.
PMID: 20090780
No abstract available.
3.
Gu T, Popova L, Reeves C, Nardone J, Macneill J, Rush J, et al.
Leukemia
. 2007 Jan;
21(3):563-6.
PMID: 17252008
No abstract available.
4.
Gingras A, Raught B, Gygi S, Niedzwiecka A, Miron M, Burley S, et al.
Genes Dev
. 2001 Nov;
15(21):2852-64.
PMID: 11691836
In most instances, translation is regulated at the initiation phase, when a ribosome is recruited to the 5' end of an mRNA. The eIF4E-binding proteins (4E-BPs) interdict translation initiation by...
5.
Kansra V, Groves C, Gutierrez-Ramos J, Polakiewicz R
J Biol Chem
. 2001 Jul;
276(34):31831-8.
PMID: 11432847
Fractalkine, the first member of the CX(3)C chemokine family, induces leukocyte chemotaxis through activation of its high affinity receptor, CX(3)CR1. Like other chemokine receptors, CX(3)CR1 is coupled to a pertussis...
6.
Gingras A, Gygi S, Raught B, Polakiewicz R, Abraham R, Hoekstra M, et al.
Genes Dev
. 1999 Jun;
13(11):1422-37.
PMID: 10364159
The multisubunit eukaryotic translation initiation factor (eIF) 4F recruits 40S ribosomal subunits to the 5' end of mRNA. The eIF4F subunit eIF4E interacts directly with the mRNA 5' cap structure....
7.
Polakiewicz R, Schieferl S, Gingras A, Sonenberg N, Comb M
J Biol Chem
. 1998 Aug;
273(36):23534-41.
PMID: 9722592
The mu-opioid receptor mediates the analgesic and addictive properties of morphine. Despite the clinical importance of this G-protein-coupled receptor and many years of pharmacological research, few intracellular signaling mechanisms triggered...
8.
Polakiewicz R, Schieferl S, Dorner L, Kansra V, Comb M
J Biol Chem
. 1998 Jun;
273(20):12402-6.
PMID: 9575195
The mu-opioid receptor mediates not only the beneficial painkilling effects of opiates like morphine but also the detrimental effects of chronic exposure such as tolerance and dependence. Different studies have...
9.
Luoh S, Bain P, Polakiewicz R, Goodheart M, Gardner H, Jaenisch R, et al.
Development
. 1997 Jun;
124(11):2275-84.
PMID: 9187153
The zinc-finger proteins ZFX and ZFY, encoded by genes on the mammalian X and Y chromosomes, have been speculated to function in sex differentiation, spermatogenesis, and Turner syndrome. We derived...
10.
Rosen H, Krichevsky A, Polakiewicz R, Benzakine S, Bar-Shavit Z
Mol Endocrinol
. 1995 Nov;
9(11):1621-31.
PMID: 8584038
Proenkephalin (PENK), a classically defined opioid gene, was originally thought to be expressed almost exclusively in the mature nervous and neuroendocrine systems. In the last few years, it was demonstrated,...