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R D Polakiewicz

Explore the profile of R D Polakiewicz including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 1275
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11.
Polakiewicz R, Munroe D, Sait S, Tycowski K, Nowak N, Shows T, et al.
Genomics . 1995 Jan; 25(2):577-80. PMID: 7789996
The mammalian ribosome is a massive structure composed of 4 RNA species and about 80 different proteins. One of these ribosomal proteins, S3, appears to function not only in translation...
12.
Behar O, Ovadia H, Polakiewicz R, Rosen H
Endocrinology . 1994 Jan; 134(1):475-81. PMID: 8275961
The proenkephalin gene encodes a family of neuropeptides that was originally identified in brain tissue and adrenal glands. Recently, it was shown that proenkephalin is also expressed in cultured lymphoid...
13.
Meiner Z, Halimi M, Polakiewicz R, Prusiner S, Gabizon R
Neurology . 1992 Jul; 42(7):1355-60. PMID: 1352391
The prion protein (PrP) gene on chromosome 20 encodes a protein designated PrPC. An abnormal, protease-resistant isoform of PrPC, denoted PrPCJD or PrPSc, is present in the brains of patients...
14.
Polakiewicz R, Behar O, Comb M, Rosen H
Mol Endocrinol . 1992 Mar; 6(3):399-408. PMID: 1584216
Proenkephalin, a classically defined opioid encoding gene, is transiently expressed in nondifferentiated mesodermal cells during organogenesis. We examined the hypothesis that this expression is associated with mesenchymal cell proliferation. For...
15.
Behar O, Ovadia H, Polakiewicz R, Abramsky O, Rosen H
Endocrinology . 1991 Aug; 129(2):649-55. PMID: 1855463
Proenkephalin A (PEA) encodes a group of small peptides known to function as neurotransmitters, neuromodulators, and neurohormones in the nervous and neuroendocrine systems. This gene has been shown to be...
16.
Rosen H, Polakiewicz R, Benzakine S, Bar-Shavit Z
Proc Natl Acad Sci U S A . 1991 May; 88(9):3705-9. PMID: 2023920
Enkephalins, a group of small peptides with opiate-like activity, have been defined originally as neuropeptides. Recent reports showed, using in situ hybridization, that the enkephalin-encoding gene, proenkephalin A (pEnkA), is...
17.
Rosen H, Polakiewicz R, Simantov R
Biochem Biophys Res Commun . 1990 Sep; 171(2):722-8. PMID: 1698363
Proenkephalin A (PEA) gene was found to be expressed in primary, secondary and tertiary cultures of rat fibroblasts. The 1.4 kb PEA mRNA was detected by Northern blot analysis. The...
18.
Polakiewicz R, Rosen H
Mol Cell Biol . 1990 Feb; 10(2):736-42. PMID: 2300059
Proenkephalin A (PEA), a neuropeptide-encoding gene, is widely expressed in the nervous and endocrine systems. Recently, we demonstrated that in addition to its abundance in fetal brain tissue; PEA is...
19.
Keshet E, Polakiewicz R, Itin A, Ornoy A, Rosen H
EMBO J . 1989 Oct; 8(10):2917-23. PMID: 2583085
Proenkephalin A (PEA) encodes several neuropeptides with an opioid activity, as well as other peptides with as yet unknown functions. As an initial step toward finding possible roles for PEA...
20.
Rosen H, Polakiewicz R
Brain Res . 1989 Jul; 493(2):380-4. PMID: 2765905
Lead, an environmental pollutant, has been long recognized as a neurotoxic agent. Several reports have recently described behavioral disturbances caused by low level lead exposure. Lead-induced changes in neurotransmitter metabolism...