Premlata Shankar
Overview
Explore the profile of Premlata Shankar including associated specialties, affiliations and a list of published articles.
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47
Citations
3141
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Recent Articles
1.
Song E, Lee S, Dykxhoorn D, Novina C, Zhang D, Crawford K, et al.
J Virol
. 2023 Oct;
97(10):e0093623.
PMID: 37830822
No abstract available.
2.
Chaudhuri D, Lu T, Jacob B, Abraham S, Shankar P, Poss M, et al.
J Control Release
. 2023 May;
359:26-32.
PMID: 37236320
The CXCR4 chemokine is a key molecular regulator of many biological functions controlling leukocyte functions during inflammation and immunity, and during embryonic development. Overexpression of CXCR4 is also associated with...
3.
Bharaj P, Ye C, Petersen S, Wang Q, Hu B, Manjunath N, et al.
Heliyon
. 2018 Mar;
4(2):e00545.
PMID: 29527580
We have previously reported that overexpression of Programmed Death -1 Homolog (PD-1H) in human monocytes leads to activation and spontaneous secretion of multiple pro inflammatory cytokines. Here we evaluate changes...
4.
Yi G, Xu X, Abraham S, Petersen S, Guo H, Ortega N, et al.
EBioMedicine
. 2017 Oct;
25:87-94.
PMID: 29033368
A DNA vaccine encoding prM and E protein has been shown to induce protection against Zika virus (ZIKV) infection in mice and monkeys. However, its effectiveness in humans remains undefined....
5.
Abraham S, Guo H, Choi J, Ye C, Thomas M, Ortega N, et al.
Heliyon
. 2017 Apr;
3(4):e00276.
PMID: 28409183
IL-10 is a crucial anti-inflammatory cytokine which can also exert a seemingly divergent immunostimulatory effects under certain conditions. We found high levels of the cytokine in a xenogeneic GVHD model...
6.
Abraham S, Choi J, Ortega N, Zhang J, Shankar P, Swamy N
Oncotarget
. 2016 Oct;
7(48):78412-78420.
PMID: 27729616
Because endogenous interferon type I (IFN-I) produced by HIV-1 infection might complicate the analysis of therapeutically administered IFN-I, we tested different humanized mouse models for induction of IFN-I during HIV-1...
7.
Swamy M, Wu H, Shankar P
Adv Drug Deliv Rev
. 2016 Mar;
103:174-186.
PMID: 27013255
RNA interference (RNAi) provides a powerful tool to silence specific gene expression and has been widely used to suppress host factors such as CCR5 and/or viral genes involved in HIV-1...
8.
Dang Y, Jia G, Choi J, Ma H, Anaya E, Ye C, et al.
Genome Biol
. 2015 Dec;
16:280.
PMID: 26671237
Background: Single-guide RNA (sgRNA) is one of the two key components of the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 genome-editing system. The current commonly used sgRNA structure has a...
9.
Yi G, Tu X, Bharaj P, Guo H, Zhang J, Shankar P, et al.
Mol Ther
. 2015 Jun;
23(10):1663-70.
PMID: 26061648
Attempts at eliciting neutralizing antibodies against human immunodeficiency virus (HIV)-1 have generally failed. Computationally designed epitope-scaffold platforms allow transplantation of structural epitopes to scaffold proteins. Human rhinovirus (HRV) allows such...
10.
Abraham S, Choi J, Ye C, Manjunath N, Shankar P
Clin Immunol
. 2014 Dec;
156(1):58-64.
PMID: 25463432
Although patients with GVHD have elevated serum levels of IL10, whether its role is protective or pathogenic remains unclear. Here, we used a humanized mouse model to study the role...