Pras Pathmanathan
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Explore the profile of Pras Pathmanathan including associated specialties, affiliations and a list of published articles.
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44
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1143
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Recent Articles
1.
Dautel K, Agyingi E, Pathmanathan P
BMC Med Inform Decis Mak
. 2024 Nov;
24(1):322.
PMID: 39482697
Background: Numerous medical resource demand models have been created as tools for governments or hospitals, aiming to predict the need for crucial resources like ventilators, hospital beds, personal protective equipment...
2.
Aycock K, Battisti T, Peterson A, Yao J, Kreuzer S, Capelli C, et al.
Front Med (Lausanne)
. 2024 Aug;
11:1433372.
PMID: 39188879
Computational models of patients and medical devices can be combined to perform an clinical trial (ISCT) to investigate questions related to device safety and/or effectiveness across the total product life...
3.
Pathmanathan P, Aycock K, Badal A, Bighamian R, Bodner J, Craven B, et al.
PLoS Comput Biol
. 2024 Aug;
20(8):e1012289.
PMID: 39116026
In silico clinical trials (ISCTs) are an emerging method in modeling and simulation where medical interventions are evaluated using computational models of patients. ISCTs have the potential to provide cost-effective,...
4.
Galappaththige S, Pathmanathan P, Gray R
Front Physiol
. 2023 Jul;
14:1074527.
PMID: 37485068
There are a variety of difficulties in evaluating clinical cardiac mapping systems, most notably the inability to record the transmembrane potential throughout the entire heart during patient procedures which prevents...
5.
Cooper F, Baker R, Bernabeu M, Bordas R, Bowler L, Bueno-Orovio A, et al.
J Open Source Softw
. 2023 May;
5(47):1848.
PMID: 37192932
Chaste (Cancer, Heart And Soft Tissue Environment) is an open source simulation package for the numerical solution of mathematical models arising in physiology and biology. To date, Chaste development has...
6.
Dautel K, Agyingi E, Pathmanathan P
PLoS Comput Biol
. 2023 Mar;
19(3):e1010968.
PMID: 36989251
Mathematical models have been an important tool during the COVID-19 pandemic, for example to predict demand of critical resources such as medical devices, personal protective equipment and diagnostic tests. Many...
7.
Ahmed K, Pathmanathan P, Kabadi S, Drgon T, Morrison T
Ann Biomed Eng
. 2022 Dec;
51(1):6-9.
PMID: 36547742
No abstract available.
8.
Kanal V, Pathmanathan P, Hahn J, Kramer G, Scully C, Bighamian R
Sci Rep
. 2022 Dec;
12(1):21463.
PMID: 36509856
Physiological closed-loop controlled (PCLC) medical devices monitor and automatically adjust the patient's condition by using physiological variables as feedback, ideally with minimal human intervention to achieve the target levels set...
9.
Galappaththige S, Gray R, Mendonca Costa C, Niederer S, Pathmanathan P
PLoS Comput Biol
. 2022 Oct;
18(10):e1010541.
PMID: 36215228
Reliable and robust simulation of individual patients using patient-specific models (PSMs) is one of the next frontiers for modeling and simulation (M&S) in healthcare. PSMs, which form the basis of...
10.
Santiago A, Butakoff C, Eguzkitza B, Gray R, May-Newman K, Pathmanathan P, et al.
PLoS Comput Biol
. 2022 Jun;
18(6):e1010141.
PMID: 35696442
Background: Left ventricular assist devices (LVADs) are implantable pumps that act as a life support therapy for patients with severe heart failure. Despite improving the survival rate, LVAD therapy can...