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Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences

Philosophical Transactions, Series A is a renowned academic journal that focuses on mathematical, physical, and engineering sciences. It publishes cutting-edge research articles, reviews, and perspectives from leading scholars worldwide. With a rich history dating back to 1665, this esteemed journal serves as a platform for disseminating groundbreaking discoveries and advancements in these disciplines, fostering interdisciplinary dialogue and promoting scientific progress.

Details
Abbr. Philos Trans A Math Phys Eng Sci
Start 1996
End Continuing
Frequency Twenty four no. a year, 2008-
p-ISSN 1364-503X
e-ISSN 1471-2962
Country United Kingdom
Language English
Metrics
h-index / Ranks: 777 193
SJR / Ranks: 4681 870
CiteScore / Ranks: 2208 8.10
JIF / Ranks: 1573 5.0
Recent Articles
1.
Bottcher L, Fonseca L, Laubenbacher R
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240228. PMID: 40078154
The objective of precision medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology...
2.
Tsaneva-Atanasova K, Pederzanil G, Laviola M
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240207. PMID: 40078153
In this opinion piece, we examine the pivotal role that uncertainty quantification (UQ) plays in informing clinical decision-making processes. We explore challenges associated with healthcare data and the potential barriers...
3.
Dadashova K, Smith R, Haider M, Reich B
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240219. PMID: 40078152
Physiologically based pharmacokinetic (PBPK) models use a mechanistic approach to delineate the processes of the absorption, distribution, metabolism and excretion of biological substances in various species. These models generally comprise...
4.
Kimpton L, Paun L, Colebank M, Volodina V
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240232. PMID: 40078151
Uncertainty quantification (UQ) is an essential aspect of computational modelling and statistical prediction. Multiple applications, including geophysics, climate science and aerospace engineering, incorporate UQ in the development and translation of...
5.
De Florio M, Zou Z, Schiavazzi D, Karniadakis G
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240221. PMID: 40078150
When predicting physical phenomena through simulation, quantification of the total uncertainty due to multiple sources is as crucial as making sure the underlying numerical model is accurate. Possible sources include...
6.
Paun L, Colebank M, Husmeier D
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240222. PMID: 40078149
Computational modelling of the cardiovascular system is a promising future direction for patient-specific healthcare. However, the computational cost of these simulators is a bottleneck for their practical use in clinic...
7.
Shuttleworth J, Lei C, Windley M, Hill A, Preston S, Mirams G
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240211. PMID: 40078148
Mathematical models are increasingly being relied upon to provide quantitatively accurate predictions of cardiac electrophysiology. Many such models concern the behaviour of particular subcellular components (namely, ion channels) which, together,...
8.
Richter J, Nitzler J, Pegolotti L, Menon K, Biehler J, Wall W, et al.
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240223. PMID: 40078147
Bayesian boundary condition (BC) calibration approaches from clinical measurements have successfully quantified inherent uncertainties in cardiovascular fluid dynamics simulations. However, estimating the posterior distribution for all BC parameters in three-dimensional...
9.
Del Core L, Mirams G
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240224. PMID: 40078146
Mathematical models of ion channel gating describe the changes in ion channel configurations due to the electrical activity of the cell membrane. Experimental findings suggest that ion channels behave randomly,...
10.
Bajaj S, Thompson R, Lambert B
Philos Trans A Math Phys Eng Sci . 2025 Mar; 383(2292):20240357. PMID: 40078145
During infectious disease outbreaks, delays in case reporting mean that the time series of cases is unreliable, particularly for those cases occurring most recently. This means that real-time estimates of...