Jonathan P Whiteley
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Explore the profile of Jonathan P Whiteley including associated specialties, affiliations and a list of published articles.
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34
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264
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Recent Articles
1.
Whiteley J, Brown C, Gaffney E
J Mech Behav Biomed Mater
. 2024 Jun;
156:106575.
PMID: 38824865
Articular cartilage tissue exhibits a spatial dependence in material properties that govern mechanical behaviour. A mathematical model of cartilage tissue under one dimensional confined compression testing is developed for normal...
2.
Whiteley J, Brown C, Gaffney E
Math Med Biol
. 2022 Jun;
39(3):251-298.
PMID: 35679151
In skeletal joints two layers of adjacent cartilage are often in relative motion. The individual cartilage layers are often modelled as a poroviscoelastic material. To model the relative motion, noting...
3.
Ambuehl A, Whiteley J
Math Biosci
. 2021 Apr;
337:108618.
PMID: 33878304
Many physical phenomena in biology and physiology are described by mathematical models that comprise a system of initial value ordinary differential equations. Each differential equation may often be written as...
4.
Whiteley J, Gaffney E
Math Med Biol
. 2020 Feb;
37(3):389-428.
PMID: 32072158
Swelling pressure in the interstitial fluid within the pores of cartilage tissue is known to have a significant effect on the rheology of cartilage tissue. The swelling pressure varies rapidly...
5.
Whiteley J
Math Med Biol
. 2019 Nov;
37(2):262-302.
PMID: 31680135
Tissue level cardiac electrophysiology is usually modelled by the bidomain equations, or the monodomain simplification of the bidomain equations. One assumption made when deriving the bidomain equations is that both...
6.
Chen M, Whiteley J, Please C, Ehlicke F, Waters S, Byrne H
J Tissue Eng
. 2019 May;
10:2041731419842431.
PMID: 31040937
A key step in the tissue engineering of articular cartilage is the chondrogenic differentiation of mesenchymal stem cells (MSCs) into chondrocytes (native cartilage cells). Chondrogenesis is regulated by transforming growth...
7.
Klika V, Whiteley J, Brown C, Gaffney E
Biomech Model Mechanobiol
. 2019 Feb;
18(4):953-968.
PMID: 30729390
Articular cartilage is a complex, anisotropic, stratified tissue with remarkable resilience and mechanical properties. It has been subject to extensive modelling as a multiphase medium, with many recent studies examining...
8.
Bowler L, Gavaghan D, Mirams G, Whiteley J
Bull Math Biol
. 2018 Oct;
81(1):7-38.
PMID: 30291590
Distinct electrophysiological phenotypes are exhibited by biological cells that have differentiated into particular cell types. The usual approach when simulating the cardiac electrophysiology of tissue that includes different cell types...
9.
Roberts P, Gaffney E, Whiteley J, Luthert P, Foss A, Byrne H
Invest Ophthalmol Vis Sci
. 2018 Apr;
59(3):1238-1249.
PMID: 29625444
Purpose: To determine whether the oxygen toxicity hypothesis can explain the distinctive spatio-temporal patterns of retinal degeneration associated with human retinitis pigmentosa (RP) and to predict the effects of antioxidant...
10.
Chen M, Whiteley J, Please C, Schwab A, Ehlicke F, Waters S, et al.
J Theor Biol
. 2017 Dec;
439:1-13.
PMID: 29203122
The differentiation of mesenchymal stem cells (MSCs) into chondrocytes (native cartilage cells), or chondrogenesis, is a key step in the tissue engineering of articular cartilage, where the motility and high...