Prajwal Gurung
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Explore the profile of Prajwal Gurung including associated specialties, affiliations and a list of published articles.
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60
Citations
3455
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Recent Articles
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Patel R, Jha A, Jain A, Verma A, Saini S, Muia J, et al.
Blood Adv
. 2025 Jan;
9(6):1330-1341.
PMID: 39787593
Respiratory tract infections (RTIs) caused by bacteria or viruses are associated with stroke severity. Recent studies have revealed an imbalance in the von Willebrand factor (VWF)-ADAMTS13 (a disintegrin and metalloproteinase...
3.
Saini S, Gurung P
Immunol Rev
. 2024 Oct;
329(1):e13409.
PMID: 39425547
Radiation, a universal component of Earth's environment, is categorized into non-ionizing and ionizing forms. While non-ionizing radiation is relatively harmless, ionizing radiation possesses sufficient energy to ionize atoms and disrupt...
4.
Gehrke E, Pandey A, Thompson J, Bhattarai S, Gurung P, Hsu Y, et al.
Front Med (Lausanne)
. 2024 Jun;
11:1347599.
PMID: 38938378
Purpose: Previous studies have reported Caspase-1 () is upregulated in mouse models of Juvenile X-linked Retinoschisis (XLRS), however no functional role for in disease progression has been identified. We performed...
5.
Wang Y, Gao J, Sakaguchi T, Maretzky T, Gurung P, Narayanan N, et al.
Cells
. 2024 Apr;
13(7.
PMID: 38607004
Leucine-rich repeat kinase 2 (LRRK2) is a serine-threonine protein kinase belonging to the ROCO protein family. Within the kinase domain of LRRK2, a point mutation known as LRRK2 G2019S has...
6.
Wang Y, Gao J, Sakaguchi T, Maretzky T, Gurung P, Short S, et al.
bioRxiv
. 2023 Jul;
PMID: 37425755
LRRK2 G2019S is the most prevalent variant associated with Parkinson's disease (PD), found in 1-3% of sporadic and 4-8% of familial PD cases. Intriguingly, emerging clinical studies have suggested that...
7.
Thapa P, Upadhyay S, Singh V, Boinpelly V, Zhou J, Johnson D, et al.
Eur J Med Chem Rep
. 2023 Apr;
7.
PMID: 37033416
Overactivated NLRP3 inflammasome has been shown to associate with an increasing number of disease conditions. Activation of the NLRP3 inflammasome results in caspase-1-catalyzed formation of active pro-inflammatory cytokines (IL-1β and...
8.
Mazgaeen L, Yorek M, Saini S, Vogel P, Meyerholz D, Kanneganti T, et al.
Sci Adv
. 2023 Jan;
9(1):eade3942.
PMID: 36608128
Mice with SHP1 proteins, which have a single amino acid substitution from tyrosine-208 residue to asparagine (hereafter mice), develop an autoinflammatory disease with inflamed footpads. Genetic crosses to study CD47...
9.
Marques-da-Silva C, Poudel B, Baptista R, Peissig K, Hancox L, Shiau J, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(2):e2210181120.
PMID: 36595704
Malaria, caused by parasites is a severe disease affecting millions of people around the world. undergoes obligatory development and replication in the hepatocytes, before initiating the life-threatening blood-stage of malaria....
10.
Teghanemt A, Pulipati P, Misel-Wuchter K, Day K, Yorek M, Yi R, et al.
Nat Commun
. 2022 Mar;
13(1):1477.
PMID: 35304452
The epigenetic patterns that are established during early thymic development might determine mature T cell physiology and function, but the molecular basis and topography of the genetic elements involved are...